Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale
Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale
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DOI：
10.1116/1.3151968
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发表时间：
2009-06-01
期刊：
影响因子：
2.1
通讯作者：
Ratner, Buddy D.
中科院分区：
文献类型：
--
作者：
Hucknall, Angus;Simnick, Andrew J.;Ratner, Buddy D.
介绍了用表面引发原子转移自由基聚合法合成的聚[低聚(乙二醇甲基)丙烯酸甲酯](POEGMA)聚合物刷的表面合成和图案化的新方法。这些有图案的涂层赋予生物环境中的表面“无污染”特性、蛋白质和细胞阻力。这里展示的合成POEGMA的多种路线在简单性、可靠性和大面积衬底构图能力方面提供了比以前使用的其他技术明显的优势。他们还证明，POEGMA聚合物刷子可以通过光刻、等离子灰化和反应离子刻蚀直接图案化，以高通量和重复性在大面积上创建微米和纳米级的图案，同时保持POEGMA刷子的蛋白质和细胞电阻。
In this article, the authors describe new approaches to synthesize and pattern surfaces with poly[oligo(ethylene glycol) methyl methacrylate] (POEGMA) polymer brushes synthesized by surface-initiated atom transfer radical polymerization. These patterned coatings confer "nonfouling" properties protein and cell resistance-to the surface in a biological milieu. The versatile routes for the synthesis of POEGMA demonstrated here offer clear advantages over other techniques previously used in terms of their simplicity, reliability, and ability to pattern large-area substrates. They also demonstrate that POEGMA polymer brushes can be patterned directly by photolithography, plasma ashing, and reactive ion etching to create patterns at the micro- and nanoscale over large areas with high throughput and repeatability, while preserving the protein and cell resistance of the POEGMA brush.