QUANTIFICATION OF ARTICULAR-CARTILAGE IN THE KNEE WITH PULSED SATURATION-TRANSFER SUBTRACTION AND FAT-SUPPRESSED MR-IMAGING - OPTIMIZATION AND VALIDATION
QUANTIFICATION OF ARTICULAR-CARTILAGE IN THE KNEE WITH PULSED SATURATION-TRANSFER SUBTRACTION AND FAT-SUPPRESSED MR-IMAGING - OPTIMIZATION AND VALIDATION
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DOI：
10.1148/radiology.192.2.8029420
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发表时间：
1994-08-01
期刊：
影响因子：
19.7
通讯作者：
GENANT, HK
中科院分区：
文献类型：
--
作者：
PETERFY, CG;VANDIJKE, CF;GENANT, HK
目得：为了评估的再现性和准确性的体积定量的关节软骨在膝关节测定与三维（3D）磁共振（MR）成像结合脉冲饱和转移减影（STS）或T1加权脂肪抑制（FS）imaging.MATERIALS AND METHODS：8个骨关节炎的膝盖反复成像与优化STS和FS序列。结果：STS和FS成像中软骨体积的平均高估或低估分别为0.40 mL +/- 0.11（标准差）（8.2%）和0.31 mL +/- 0.08（5.9%）。STS和FS成像的观察者内重现性误差分别为0.20-0.65 mL（3.6%-6.4%）和0.21-0.58 mL（4.2%-6.4%）。观察者间误差小于0.62 mL，误差小于7.8%。结论：STS和FS扫描图像的三维数据分析可以准确、可重复地定量膝关节软骨的体积。
PURPOSE: To assess the reproducibility and accuracy of volumetric quantifications of articular cartilage in the knee determined with three-dimensional (3D) magnetic resonance (MR) imaging combined with pulsed saturation transfer subtraction (STS) or T1-weighted fat suppression (FS) imaging.MATERIALS AND METHODS: Eight osteoarthritic knees were imaged repeatedly with optimized STS and FS sequences. Cartilage volumes were determined from 3D reconstructions of FS and STS images and by means of water displacement of surgically retrieved tissue.RESULTS: Mean over- or underestimation of cartilage volume at STS and FS imaging was 0.40 mL +/- 0.11 (standard deviation) (8.2%) and 0.31 mL +/- 0.08 (5.9%), respectively. Intraobserver reproducibility error was 0.20-0.65 mL (3.6%-6.4%) for STS and 0.21-0.58 mL (4.2%-6.4%) for FS imaging. Interobserver error was less than 0.62 mL and 7.8%.CONCLUSION: Three-dimensional data analysis of MR images acquired with STS or FS allows accurate and reproducible volumetric quantification of articular cartilage in the knee.