Prognostic factors for chronic active Epstein-Barr virus infection
Prognostic factors for chronic active Epstein-Barr virus infection
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DOI：
10.1086/367988
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发表时间：
2003-02-15
影响因子：
6.4
通讯作者：
Wakiguchi, H
中科院分区：
文献类型：
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作者：
Kimura, H;Morishima, T;Wakiguchi, H
慢性活动性 Epstein-Barr 病毒感染（CAEBV）是一种高死亡率和高发病率的疾病。为了阐明预后因素，日本进行了一项全国调查，对 82 名符合 CAEBV 标准的患者的数据进行了分析。这82名患者中，47人还活着，35人已经死亡。多变量分析显示血小板减少症和发病年龄与死亡率相关。老年患者（发病年龄大于或等于8岁）5年生存概率为0.45，年轻患者为0.94（P
Chronic active Epstein-Barr virus infection (CAEBV) is a high-mortality and high-morbidity disease. To clarify the prognostic factors, a national survey was performed in Japan, and data for 82 patients who met the criteria for CAEBV were analyzed. Of these 82 patients, 47 were alive and 35 had already died. Multivariate analysis revealed that thromobocytopenia and age at disease onset were correlated with mortality. The probability of 5-year survival was 0.45 for older patients (onset age, greater than or equal to8 years), 0.94 for younger patients (P