Renal threshold for glucose normal and in diabetics

Renal threshold for glucose normal and in diabetics
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DOI:
10.1136/bmj.1.4140.766
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发表时间:
1940-01-01
影响因子:
105.7
通讯作者:
Lawrence, RD
Lawrence, RD
中科院分区:
医学1区
文献类型:
--
作者:
Lawrence, RD

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RD LAWRENCE,MD,FRCP(来自国王学院医院糖尿病诊所)葡萄糖的肾阈值是生理学家对与肾功能有关的肾功能的极大兴趣,并且对临床医生研究和治疗糖尿病和糖尿病具有重要意义。该术语适用于血液中糖的临界浓度,它决定了糖尿的存在或不存在。低于这一水平的糖是不存在于尿中,除了在这样的最小量总是存在,并没有通过通常的测试,费林或本尼迪克特;而高于这一水平很容易可观的糖量出现在尿中。随着血糖逐渐升高,尿液中的总浓度和百分比浓度逐渐增加。肾阈值通常在170至200 mg之间。每100 ℃。cm.,而是取决于分析是对静脉血还是毛细血管血进行的。医学文献中常见的说法是”正常肾阈值为170 mg。每100 ℃。cm.,通常的含义是,任何偏离这个水平的情况都是异常的,意味着肾功能紊乱,如果不是肾结构疾病的话。
RD LAWRENCE, MD, FRCP (Fr-oml the Diabetic Clinic, King's College Hospital) The renal threshold for glucose is~ of great interest to physiologists in relation to kidney functionand of im-portance to clinicians in the study andtreatment of glycosuria and diabetes. The term is applied to the critical concentration of sugar in the blood which deter-mines the presence or absence of glycosuria. Below this level sugar is absent in the urine except in such minimal amounts as are always present and are not appreciated by the usual tests, Fehling or Benedict; while above this level easily appreciable amounts of sugar appear in the. urine and gradually increase both in total amount and in percentage concentration as the blood sugar becomes progressively higher. The renal threshold is usually found to be between 170 and 200 mg. per 100 c. cm., depending rather on whether the analysis is made on venous or capillary blood. It is a common statement in medical literature that" the normlal renal threshold is 170 mg. per 100 c. cm.," and a common implication that any deviation from this level is an abnormality, implying disorder of function if not disease of structure on the part of the kidney.