Renal threshold for glucose normal and in diabetics
Renal threshold for glucose normal and in diabetics
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DOI:
10.1136/bmj.1.4140.766
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发表时间:
1940-01-01
影响因子:
105.7
通讯作者:
Lawrence, RD
中科院分区:
文献类型:
--
作者:
Lawrence, RD
RD LAWRENCE, MD, FRCP (Fr-oml the Diabetic Clinic, King's College Hospital) The renal threshold for glucose is~ of great interest to physiologists in relation to kidney functionand of im-portance to clinicians in the study andtreatment of glycosuria and diabetes. The term is applied to the critical concentration of sugar in the blood which deter-mines the presence or absence of glycosuria. Below this level sugar is absent in the urine except in such minimal amounts as are always present and are not appreciated by the usual tests, Fehling or Benedict; while above this level easily appreciable amounts of sugar appear in the. urine and gradually increase both in total amount and in percentage concentration as the blood sugar becomes progressively higher. The renal threshold is usually found to be between 170 and 200 mg. per 100 c. cm., depending rather on whether the analysis is made on venous or capillary blood. It is a common statement in medical literature that" the normlal renal threshold is 170 mg. per 100 c. cm.," and a common implication that any deviation from this level is an abnormality, implying disorder of function if not disease of structure on the part of the kidney.