OBSERVATIONS ON THE VITAMIN-D STATE OF PREGNANT ASIAN WOMEN IN LONDON
OBSERVATIONS ON THE VITAMIN-D STATE OF PREGNANT ASIAN WOMEN IN LONDON
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DOI：
10.1111/j.1471-0528.1981.tb00931.x
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发表时间：
1981-01-01
期刊：
影响因子：
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通讯作者：
SOOD, A
中科院分区：
文献类型：
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作者：
BROOKE, OG;BROWN, IRF;SOOD, A
对居住在伦敦的115名亚洲妇女及其50名新生儿进行了妊娠期维生素D营养调查。在最后三个月开始时，平均血清25-羟基胆钙化醇（25-OHD）浓度为20.2 nmol/l，产后降至16.0 nmol/l。36%的产后妇女和32%的婴儿的25-OHD浓度检测不到（< 3 nmol/l）。这种低值通常与骨软化症和佝偻病有关。20%的妇女产后骨碱性磷酸酶同工酶升高，50%的婴儿，表明存在亚临床骨病。5名婴儿有症状性低钙血症。维生素D缺乏症最有可能发生在巴基斯坦人、印度教印度人和东非亚洲人以及素食者中。所有的英国亚洲人都应该在怀孕期间补充维生素D。
Vitamin D nutrition in pregnancy was investigated in 115 Asian women living in London, and in 50 of their newborn infants. Mean serum 25-hydroxycholecalciferol (25-OHD) concentration at the beginning of the last trimester was 20.2 nmol/l, and fell to 16.0 nmol/l postpartum. Thirty-six percent of the women postpartum and 32% of the infants had undetectable 25-OHD concentrations (< 3 nmol/l). Such low values are commonly associated with osteomalacia and rickets. The bone isoenzyme of alkaline phosphatase was elevated in 20% of the women postpartum, and in 50% of the infants, indicating the presence of subclinical bone disease. Five infants had symptomatic hypocalcemia. Vitamin D deficiency was most likely to occur in Pakistanis, Hindu Indians and East African Asians, and in vegetarians. All British Asians should receive supplementary vitamin D during pregnancy.