Demographic and Clinical Characteristics of Uveitis in Turkey: The First National Registry Report
Demographic and Clinical Characteristics of Uveitis in Turkey: The First National Registry Report
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DOI：
10.3109/09273948.2015.1108444
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发表时间：
2018-01-01
影响因子：
3.3
通讯作者：
Tugal-Tutkun, Ilknur
中科院分区：
文献类型：
--
作者：
Yalcindag, F. Nilufer;Ozdal, Pinar C.;Tugal-Tutkun, Ilknur
目的：评估白塞病眼内炎症和激光闪光光度测量之间的关系。方法：共45例患者被纳入本研究。对患者进行回顾性病历审查。闪光水平与前房细胞的等级，玻璃体细胞的存在，葡萄膜炎的并发症，荧光素血管造影scores.Results：发作组有较高的闪光强度，闪光水平在两组均高于健康对照组的值。闪烁程度与前房细胞的分级、玻璃体细胞的存在和荧光素血管造影评分有关。视神经萎缩和/或黄斑病变患者的数值也较高。较高的闪光值与较差的vision.Conclusions：Laser flare photometrics may reduce necessary of fluorescein angiography in monitoring subclinical inflammation and may be a indicator of posterior segment activity when fluorescein angiography is not applicable.目的：描述在土耳其二级和三级护理中心就诊的葡萄膜炎患者的人口统计学和临床概况。2008年11月，开始了一项全国性的葡萄膜炎患者网络登记。我们分析了从一个单一的基线注册登记vision.Results：在33个中心，6967眼4863连续患者登记的数据。发病时的平均年龄为36.6 ± 15.7（1-92）岁; 51.3%为男性。白塞病是主要的诊断（24.9%），其次是强直性脊柱炎和/或HLA-B27相关的前葡萄膜炎（9.7%），弓形虫病（7.1%），Fuchs葡萄膜炎（6.3%），和假定的疱疹性前葡萄膜炎（6.0%）。22%的眼睛视力为0.1或更差。最常见的眼部并发症是虹膜后粘连（16.2%）和白内障形成（16.2%）。结论：白塞病仍然是土耳其葡萄膜炎患者最常见的非感染性病因，而眼弓形虫病和疱疹性前葡萄膜炎是最常见的感染性葡萄膜炎实体。
Purpose: To evaluate the association between intraocular inflammation and laser flare photometry measurements in Behcet disease.Methods: In total, 45 patients were included in the study. The retrospective chart reviews of patients were performed. The flare levels were compared with the grade of anterior chamber cells, the presence of vitreous cells, the complications of uveitis, and fluorescein angiography scores.Results: The attack group had higher flare intensity; the flare levels were higher in both groups compared with the values of healthy controls. The flare levels were related to the grade of the anterior chamber cells, the presence of vitreous cells and the fluorescein angiography scores. Patients with optic atrophy and/or maculopathy also had higher values. Higher flare values were correlated with poor vision.Conclusions: Laser flare photometry may reduce the necessity of fluorescein angiography in monitoring subclinical inflammation and may be an indicator of posterior segment activity when fluorescein angiography is not applicable.Purpose: To describe the demographic and clinical profiles of uveitis patients seen at secondary and tertiary care centers in Turkey.Methods: A nationwide web-based registry of patients with uveitis was initiated in November 2008. We analyzed data from a single baseline registry-enrollment visit.Results: In 33 centers, 6967 eyes of 4863 consecutive patients were registered. The mean age at presentation was 36.6 +/- 15.7 (1-92) years; 51.3% were male. Behcet disease was the leading diagnosis (24.9%), followed by ankylosing spondylitis and/or HLA-B27-associated anterior uveitis (9.7%), toxoplasmosis (7.1%), Fuchs uveitis (6.3%), and presumed herpetic anterior uveitis (6.0%). Visual acuity was 0.1 or worse in 22% of eyes. The most common ocular complications were posterior synechiae (16.2%) and cataract formation (16.2%).Conclusions: Behcet disease is still the most common non-infectious etiology in Turkish uveitis patients, while ocular toxoplasmosis and herpetic anterior uveitis are the most common infectious uveitic entities.