A SirT'N repression for Notch.
A SirT'N repression for Notch.
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SirTN 对 Notch 的镇压。
DOI：
10.1016/j.molcel.2011.05.017
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发表时间：
2011
期刊：
影响因子：
16
通讯作者：
Jones,KatherineA
中科院分区：
文献类型：
--
作者：
Jones,KatherineA
Mulligan et al. (2011) show here that the NAD+-dependent SIRT1 (H4K16; H1K26) deacetylase acts in concert with the LSD1 (H3K4) demethylase to repress Notch-induced transcription, thus coupling two distinct histone modifications at a key epigenetic switch for Notch target genes.
