Deficits in psychological well-being and quality-of-life in minor depression: implications for DSM-V.
Deficits in psychological well-being and quality-of-life in minor depression: implications for DSM-V.
复制标题
DOI：
10.1111/j.1755-5949.2009.00108.x
复制
发表时间：
2010-08
影响因子：
5.5
通讯作者：
Mischoulon D
中科院分区：
文献类型：
--
作者：
Nierenberg AA;Rapaport MH;Schettler PJ;Howland RH;Smith JA;Edwards D;Schneider T;Mischoulon D
目的探讨轻度抑郁障碍（Min D）患者心理健康（PWB）和生活质量（QOL）的缺陷。采用生活质量、享受和满意度问卷（Q-LES-Q）和心理健康量表（PWBS）对93名进入Min D治疗研究的受试者进行评估。比较重度抑郁障碍（MDD）和规范社区样本的得分。即使受试者有轻微的抑郁严重程度，Min D样本的Q-LES-Q总分平均比社区标准低近2个标准差。在最低1%的人群中，近40%的Min D患者有Q-LES-Q评分。大多数Q-LES-Q项目的回答更接近重度抑郁症患者，而不是社区规范。在“环境掌控”和“自我接纳”的子量表中，标准化PWB的平均得分极低，在“生活目的”和“与他人的积极关系”的子量表中得分较低，但在“个人成长”和“自主”的子量表中得分处于正常范围。生活质量和PWB测量与抑郁症状严重程度的相关性较低，在有无重度抑郁症病史的情况下得分相似。轻微的抑郁存在于抑郁的连续体中。轻度抑郁症的心理健康和生活质量的缺陷是严重的。轻度抑郁是否有重度抑郁史在这些测量上没有差异。轻度抑郁症状伴Min D与生活质量和PWB环境掌握测量的严重缺陷以及自我接受不良相关。我们的研究结果表明，生活质量下降和PWB可能是有或没有重度抑郁症病史的Min D的内在认知方面。在DSM IV-TR中，如果受试者过去有过重度抑郁症发作，则可能没有必要排除轻度抑郁症的诊断。
To examine deficits in psychological well-being (PWB) and quality of life (QOL) in minor depressive disorder (Min D). Ninety-three subjects entering a treatment study for Min D were assessed using the Quality of Life, Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and the Psychological Well-Being Scale (PWBS). Scores were compared with major depressive disorder (MDD) and normative community samples. Even though subjects had mild depressive severity, Q-LES-Q total scores for the Min D sample averaged nearly 2 standard deviations below the community norm. Almost 40% of Min D cases had Q-LES-Q scores in the lowest 1% of the population. Responses to most Q-LES-Q items were closer to subjects with MDD than to community norms. Mean standardized PWB scores were extremely low for subscales of Environmental Mastery and Self-Acceptance, low for Purpose in Life and Positive Relations with Others, but within the normal range for Personal Growth and Autonomy. QOL and PWB measures had low correlations with depressive symptom severity, and scores were similar in the presence or absence of a prior history of MDD. Minor depression exists along a continuum of depression. Deficits in psychological well-being and quality-of-life in minor depression are severe. No difference in these measures if minor depression existed with or without a history of major depression. Mild depressive symptoms with Min D are associated with major deficits in QOL and PWB measures of environmental mastery and poor self-acceptance. Our findings suggest that diminished QOL and PWB may be intrinsic cognitive aspects of Min D with or without a history of MDD. It may be unnecessary in the DSM IV-TR to exclude the diagnosis of Min D if a subject has had a past episode of MDD.
登录
查看更多内容
影响因子：
17.7
作者：
Judd, LL;Rapaport, MH;Tollefson, G
通讯作者：
Tollefson, G
影响因子：
11.3
作者：
Schechter, Dianne;Endicott, Jean;Nee, John
通讯作者：
Nee, John
影响因子：
120.7
作者：
JOHNSON, J;WEISSMAN, MM;KLERMAN, GL
通讯作者：
KLERMAN, GL
影响因子：
6.6
作者：
Maier, W;Gansicke, M;Weiffenbach, O
通讯作者：
Weiffenbach, O
影响因子：
22.8
作者：
Fava, Giovanni A.;Tomba, Elena;Grandi, Silvana
通讯作者：
Grandi, Silvana