Aluminum Hydride Catalyzed Hydroboration of Alkynes
Aluminum Hydride Catalyzed Hydroboration of Alkynes
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DOI：
10.1002/anie.201609690
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发表时间：
2016-12-05
影响因子：
16.6
通讯作者：
Cowley, Michael J.
中科院分区：
文献类型：
--
作者：
Bismuto, Alessandro;Thomas, Stephen P.;Cowley, Michael J.
本文研究了以氢化铝DIBAL-H或实验室稳定的Et（3）AlDABCO为催化剂，H-Bpin为硼试剂和化学计量的氢化物源，铝催化的炔烃硼氢化反应。机理研究揭示了一种独特的反应模式，其中反应被提出通过所得烯基铝物种和HBpin之间的氢化铝化和σ键复分解进行，其作用是驱动催化循环的周转。
An aluminum-catalyzed hydroboration of alkynes using either the commercially available aluminum hydride DIBAL-H or bench-stable Et(3)AlDABCO as the catalyst and H-Bpin as both the boron reagent and stoichiometric hydride source has been developed. Mechanistic studies revealed a unique mode of reactivity in which the reaction is proposed to proceed through hydroalumination and sigma-bond metathesis between the resultant alkenyl aluminum species and HBpin, which acts to drive turnover of the catalytic cycle.