Psychological morbidity and quality of life in Australian women with early-stage breast cancer: a cross-sectional survey
Psychological morbidity and quality of life in Australian women with early-stage breast cancer: a cross-sectional survey
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DOI：
10.5694/j.1326-5377.1998.tb140220.x
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发表时间：
1998-08-17
影响因子：
11.4
通讯作者：
McKenzie, DP
中科院分区：
文献类型：
--
作者：
Kissane, DW;Clarke, DM;McKenzie, DP
目的：确定早期乳腺癌患者心理疾病的患病率并描述其生活质量。设计：横断面描述性研究1994年10月至1997年3月，来自维多利亚墨尔本的9家综合医院的患者（保守性乳房手术或乳房切除术后3个月）。303名早期乳腺癌妇女参加了一项辅助心理团体治疗的随机试验;平均年龄46岁（SD，8）。主要结果指标：精神卫生诊断和统计手册（DSM）-由莫纳什联络精神病学面试产生的第四精神病诊断;基于欧洲癌症研究与治疗组织生活质量问卷（QLQ）-C30（核心）和QLQ-BR 23的生活质量数据结果：45%的妇女（135/303）有精神障碍，42%（127）的样本有抑郁或焦虑，或两者兼而有之;轻度抑郁症82例（27.1%），焦虑症26例（8.6%），重度抑郁症29例（9.6%），恐怖症21例（6.9%）。20%的女性（61人）患有一种以上的疾病。在生活质量方面，近三分之一的女性感到自己的吸引力下降，大多数人对性活动失去了兴趣。有大量关于脱发的痛苦。13名女性（4.3%）描述了淋巴水肿症状。保乳手术与更好的身体形象相关（P
Objective: To determine the prevalence of psychological morbidity and describe quality of life in women with early-stage breast cancer.Design: Cross-sectional descriptive study (3 months after conservative breast surgery or mastectomy) of patients from nine general hospitals in Melbourne, Victoria, October 1994 to March 1997.Participants: 303 women with early-stage breast cancer entering a randomised trial of adjuvant psychological group therapy; mean age, 46 years (SD, 8).Main outcome measures: Diagnostic and Statistical Manual of Mental Health (DSM)-IV psychiatric diagnoses generated by the Monash Interview for Liaison Psychiatry; quality-of-life data based on the the European Organization for Research and Treatment of Cancer quality-of-life questionnaire (QLQ)-C30 (core) and QLQ-BR23 (breast module) instruments.Results: 45% of the women (135/303) had a psychiatric disorder; 42% (127) of the sample had depression or anxiety, or both; there was minor depression in 82 (27.1%), an anxiety disorder in 26 (8.6%), major depression in 29 (9.6%) and a phobic disorder in 21 (6.9%). 20% of women (61) had more than one disorder. On quality-of-life measures nearly one-third of the women felt less attractive and most had lost interest in sexual activity. There was substantial distress about hair loss. Symptoms of lymphoedema were described by 13 women (4.3%). Breast conservation surgery was associated with a better body image (P