Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation
Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation
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DOI：
10.1016/j.jbiomech.2004.05.006
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发表时间：
2005-04-01
影响因子：
2.4
通讯作者：
Mow, VC
中科院分区：
文献类型：
--
作者：
Huang, CY;Stankiewicz, A;Mow, VC
通过对5个人体关节的120个矩形条带和70个圆柱形试块的单轴拉伸和压缩试验，测定了人体关节软骨的拉伸和压缩性能。标本取自横跨肱骨头关节面的五个区域和关节臼上的两个区域。沿平行于分割线方向和垂直于分割线方向的两个方向获得了拉伸带材。从每个拉伸条和每个加压塞制备两个连续的厚度切片，分别对应于软骨层的浅层和中层。通过单轴拉伸实验和约束压缩实验分别测定了软骨的平衡拉伸模数和压缩骨料模数。拉伸模数随深度和方向相对于局部分割线方向有显著差异。肱骨头关节软骨的张力明显高于肩臼软骨。肩关节软骨的压缩模数在肩部浅层和中层之间有显著差异。此外，在有限应变下，拉伸和压缩应力-应变响应表现出非线性，而在0%应变下，拉伸弹性模量与压缩骨料弹性模量相差两个数量级，表现出高度的拉伸-压缩非线性。本研究揭示了人关节软骨力学特性的复杂性，在同一关节内表现出各向异性、不均质性和拉伸-压缩非线性。观察到的人类关节软骨拉伸性能的差异表明，关节突可能比肩关节更容易发生软骨退变。(C)2004爱思唯尔有限公司。保留所有权利。
The tensile and compressive properties of human glenohumeral cartilage were determined by testing 120 rectangular strips in uniaxial tension and 70 cylindrical plugs in confined compression, obtained from five human glenohumeral joints. Specimens were harvested from five regions across the articular surface of the humeral head and two regions on the glenoid. Tensile strips were obtained along two orientations, parallel and perpendicular to the split-line directions. Two serial slices through the thickness, corresponding to the superficial and middle zones of the cartilage layers, were prepared from each tensile strip and each compressive plug. The equilibrium tensile modulus and compressive aggregate modulus of cartilage were determined from the uniaxial tensile and confined compression tests, respectively. Significant differences in the tensile moduli were found with depth and orientation relative to the local split-line direction. Articular cartilage of the humeral head was significantly stiffer in tension than that of the glenoid. There were significant differences in the aggregate compressive moduli of articular cartilage between superficial and middle zones in the humeral head. Furthermore, tensile and compressive stress-strain responses exhibited nonlinearity under finite strain, while the tensile modulus differed by up to two orders of magnitude from the compressive aggregate modulus at 0% strain, demonstrating a high degree of tension-compression nonlinearity. The complexity of the mechanical properties of human glenohumeral cartilage was exposed in this study, showing anisotropy, inhomogeneity, and tension-compression nonlinearity within the same joint. The observed differences in the tensile properties of human glenohumeral cartilage suggest that the glenoid may be more susceptible to cartilage degeneration than the humeral head. (c) 2004 Elsevier Ltd. All rights reserved.