Nanoarchaeal Origin of Histone H3?
Nanoarchaeal Origin of Histone H3?
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DOI:
10.1128/jb.01431-08
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发表时间:
2009-02-01
影响因子:
3.2
通讯作者:
Huber, Harald
中科院分区:
文献类型:
--
作者:
Friedrich-Jahn, Ulrike;Aigner, Johanna;Huber, Harald
NEQ288, one of two archaeal histones in Nanoarchaeum equitans, has a unique four-residue insertion that closely resembles an insertion in the eukaryotic histone H3 lineage. NEQ288 bound DNA but did not compact DNA in vitro in the absence of NEQ348, the second N. equitans archaeal histone. The properties of NEQ288 suggest an intermediate between the archaeal and H3 histone lineages and an evolutionary step toward the now-mandatory assembly of eukaryotic histones into heterodimers.