Macrolide resistance of Mycoplasma pneumoniae, South Korea, 2000-2011.

Macrolide resistance of Mycoplasma pneumoniae, South Korea, 2000-2011.
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DOI:
10.3201/eid1908.121455
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发表时间:
2013-08
影响因子:
11.8
通讯作者:
Lee JH
Lee JH
中科院分区:
医学2区
文献类型:
--
作者:
Hong KB;Choi EH;Lee HJ;Lee SY;Cho EY;Choi JH;Kang HM;Lee J;Ahn YM;Kang YH;Lee JH

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在韩国,2000 年至 2011 年期间收集的 255/2,089 份呼吸道标本中检出肺炎支原体; 80个分离株携带23S rRNA基因突变,69/123个具有该突变的培养阳性样本对5种大环内酯类药物耐药。 2000年至2011年间,该突变的患病率大幅增加。这些发现对于支原体肺炎儿童的治疗具有重要意义。
In Korea, Mycoplasma pneumoniae was detected in 255/2,089 respiratory specimens collected during 2000–2011; 80 isolates carried 23S rRNA gene mutations, and 69/123 culture-positive samples with the mutation were resistant to 5 macrolides. During 2000–2011, prevalence of the mutation increased substantially. These findings have critical implications for the treatment of children with mycoplasma pneumonia.