Peripherally Physiological Responses to External Emotions and Their Transitions in Bipolar I Disorder With and Without Hypersexuality
Peripherally Physiological Responses to External Emotions and Their Transitions in Bipolar I Disorder With and Without Hypersexuality
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伴或不伴性欲亢进的 I 型双相情感障碍对外部情绪的外周生理反应及其转变
DOI：
10.1007/s10508-019-01615-8
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发表时间：
2020-03
影响因子：
3.8
通讯作者：
Wang Wei
中科院分区：
文献类型：
--
作者：
Wang Chu;Shao Xu;Jia Yanli;Ho Roger C.;Harris Keith M.;Wang Wei
性欲亢进与精神疾病（如躁狂症）有关;然而，目前尚不清楚是否双相I型障碍（BW）或不（BO）性欲亢进表现出不同的反应，外部情绪刺激和他们的过渡，由图片和声音的相同领域。在21名BW患者、20名BO患者和41名健康志愿者中，我们进行了测谎仪测试（心电图、肌电图、眼电图和皮肤电反应），以测量从初始情绪（即，外部厌恶、色情、恐惧、快乐、中性和悲伤）到不一致的情绪（其余五种），再到初级情绪（重复初级）。我们还评估了参与者的躁狂，轻躁狂和抑郁的并发状态。当中性情绪作为非一致性情绪时，当从重复引物的反应中减去对引物的反应时，BW的心率差异大于对照组，或者当从重复引物的反应中减去对引物的反应时，BW的心率差异大于对照组。当从重复引物中性反应中减去对非一致性快乐的反应时，BW中咬肌肌电活动的差异低于BO和对照组，并且当从重复引物色情反应中减去对非一致性中性反应时，BW中咬肌肌电活动的差异低于BO。眼球运动的差异是更大的BW比BO和控制时，反应的不一致的悲伤被减去反应的重复引物中性。当从对不一致的中性反应中减去对引物快乐的反应时，心率差异与BO中的躁狂呈负相关。BW和BO患者表现出不同的外部情绪及其过渡，特别是关于色情和悲伤，这可能是两个双相I型障碍亚型独特的病理生理过程的特征。
Hypersexuality is associated with psychiatric disorders such as mania; however, it remains unclear whether bipolar I disorder with (BW) or without (BO) hypersexuality demonstrates different responses to external emotional stimuli and their transitions that were composed of pictures and sounds of same domain. In 21 BW patients, 20 BO patients, and 41 healthy volunteers, we administered polygraph tests (electrocardiogram, electromyogram, electrooculogram, and galvanic skin response) to measure transitions from a primer emotion (i.e., external disgust, erotica, fear, happiness, neutral, and sadness) to a noncongruent emotion (out of the remaining five) and to the primer emotion again (repeat-primer). We also evaluated participants’ concurrent states of mania, hypomania, and depression. With neutral as the noncongruent emotion, the heart rate difference in BW was greater than in controls when responses to the primer erotica were subtracted from responses to the repeat-primer erotica, or when to the primer sadness were subtracted from the repeat-primer sadness. The difference of the masseter electromyographic activity in BW was lower than in BO and controls when responses to the noncongruent happiness were subtracted from responses to the repeat-primer neutral, and was lower than in BO when to the noncongruent neutral were subtracted from the repeat-primer erotica. The eyeball movement difference was greater in BW than in BO and controls when responses to the noncongruent sadness were subtracted from responses to the repeat-primer neutral. The heart rate difference when responses to the primer happiness were subtracted from responses to the noncongruent neutral was negatively correlated with mania in BO. BW and BO patients behaved differently to external emotions and their transitions, particularly regarding erotica and sadness, which might characterize unique pathophysiological processes of the two bipolar I disorder subtypes.
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影响因子：
3.8
作者：
K. Skegg;S. Nada-Raja;N. Dickson;C. Paul
通讯作者：
K. Skegg;S. Nada-Raja;N. Dickson;C. Paul
DOI：
10.1016/s0013-7006(08)80620-3
发表时间：
2008-06
期刊：
L'Encephale
影响因子：
--
作者：
H. Lôo
通讯作者：
H. Lôo
DOI：
10.1080/10720160802288829
发表时间：
2008-08
期刊：
Sexual Addiction & Compulsivity
影响因子：
--
作者：
J. Hook;Jan P. Hook;Steven Hines
通讯作者：
J. Hook;Jan P. Hook;Steven Hines
DOI：
--
发表时间：
2011
期刊：
--
影响因子：
--
作者：
Bernd Figner;R. O. Murphy
通讯作者：
Bernd Figner;R. O. Murphy
DOI：
10.4236/psych.2014.52024
发表时间：
2014-02
期刊：
Psychology
影响因子：
--
作者：
N. Paunović;J. Hallberg
通讯作者：
N. Paunović;J. Hallberg