Survival of rabbit haemorrhagic disease virus (RHDV) in the environment
Survival of rabbit haemorrhagic disease virus (RHDV) in the environment
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DOI：
10.1017/s0950268805003766
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发表时间：
2005-08-01
影响因子：
4.2
通讯作者：
Morris, RS
中科院分区：
文献类型：
--
作者：
Henning, J;Meers, J;Morris, RS
对兔出血症病毒（RHDV）在环境中的持久性进行了研究。将病毒浸渍到两种载体材料（棉带和牛肝）上，并在新西兰秋季暴露于牧场的环境条件下。在1、10、44和91天后采集样品，通过经口接种易感的11- 14周龄新西兰白色兔测定病毒的活力。RHDV感染的证据是基于临床和病理学体征和/或血清转化为RHDV。浸渍在棉胶带上的病毒在暴露10天时是活的，但在44天时不是，而在牛肝中，它在91天时仍然是活的。本研究的结果表明，动物组织如兔尸体中的RHDV可在野外存活至少3个月，而直接暴露于环境条件的病毒，如干燥的排泄病毒，存活时间不到1个月。因此，RHDV在死亡动物组织中的存活可能提供一个持久的病毒库，这可能在长时间延迟后引发新的疾病爆发。
A study was conducted to investigate the persistence of rabbit haemorrhagic disease virus (RHDV) in the environment. Virus was impregnated onto two carrier materials (cotton tape and bovine liver) and exposed to environmental conditions on pasture during autumn in New Zealand. Samples were collected after 1, 10, 44 and 91 days and the viability of the virus was determined by oral inoculation of susceptible 11- to 14-week-old New Zealand White rabbits. Evidence of RHDV infection was based on clinical and pathological signs and/or seroconversion to RHDV. Virus impregnated on cotton tape was viable at 10 days of exposure but not at 44 days, while in bovine liver it was still viable at 91 days. The results of this study suggest that RHDV in animal tissues such as rabbit carcasses can survive for at least 3 months in the field, while virus exposed directly to environmental conditions, such as dried excreted virus, is viable for a period of less than I month. Survival of RHDV in the tissues of dead animals could, therefore, provide a persistent reservoir of virus, which could initiate new outbreaks of disease after extended delays.