A Synthetic Total Impulse Response Characterization Method for Correction of Hand-Held Optoacoustic Images
A Synthetic Total Impulse Response Characterization Method for Correction of Hand-Held Optoacoustic Images
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DOI：
10.1109/tmi.2020.2989236
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发表时间：
2020-10-01
影响因子：
10.6
通讯作者：
Ntziachristos, Vasilis
中科院分区：
文献类型：
--
作者：
Chowdhury, Kaushik Basak;Prakash, Jaya;Ntziachristos, Vasilis
光声层析成像系统的冲激响应取决于系统的几个组成部分，这些组成部分的特性会影响重建图像的质量。到目前为止，这些系统组件对重建质量的影响尚未详细考虑。在这里，我们结合联合收割机稀疏测量的总脉冲响应（TIR）的几何声学模型，以获得完整的表征TIR的手持光声层析成像系统与凹有限视图采集几何。然后，我们使用这种合成TIR来重建来自幻影和健康人类志愿者的数据，证明图像分辨率和保真度的改善。具有TIR校正的光声层析重建的更高精度进一步提高了手持式光声层析系统的诊断能力。
The impulse response of optoacoustic (photoacoustic) tomographic imaging system depends on several system components, the characteristics of which can influence the quality of reconstructed images. The effect of these system components on reconstruction quality have not been considered in detail so far. Here we combine sparse measurements of the total impulse response (TIR) with a geometric acoustic model to obtain a full characterization of the TIR of a handheld optoacoustic tomography system with concave limited-view acquisition geometry. We then use this synthetic TIR to reconstruct data from phantoms and healthy human volunteers, demonstrating improvements in image resolution and fidelity. The higher accuracy of optoacoustic tomographic reconstruction with TIR correction further improves the diagnostic capability of handheld optoacoustic tomographic systems.