High prevalence of malnutrition and nutrition impact symptoms in older patients with cancer: Results of a Brazilian multicenter study
High prevalence of malnutrition and nutrition impact symptoms in older patients with cancer: Results of a Brazilian multicenter study
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DOI：
10.1002/cncr.32437
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发表时间：
2019-09-09
期刊：
影响因子：
6.2
通讯作者：
Peres, Wilza A. F.
中科院分区：
文献类型：
--
作者：
de Pinho, Nivaldo B.;Martucci, Renata B.;Peres, Wilza A. F.
背景癌症患者的营养不良是与不良临床结局相关的独立因素。本研究的目的是评估巴西不同年龄组癌症患者营养不良的患病率，并确定与营养影响症状（NIS）的相关性。方法在这项观察性、横断面、多中心研究中，作者评估了4783例年龄≥ 20岁的癌症患者，这些患者在巴西的45家公立医院住院。营养状况、营养风险和NIS使用患者生成的主观总体评估进行评价。结果超过四分之一（25.5%）的参与者年龄≥ 65岁。在≥ 65岁的患者中，中度/疑似和重度营养不良的患病率为55%，51 - 64岁的患者为45.4%，≥ 65岁的患者为36.1%，无食欲（比值比[OR]，1.90; 95%CI，1.62-2.22; P <0.05）和口干（OR，1.40; 95%CI，1.1-1.67; P <0.05）。在51 - 64岁的患者中，与年龄≥ 65岁的癌症患者相比。50岁以上人群NIS发生率高于50岁以上人群
Background Malnutrition in cancer is an independent factor associated with negative clinical outcomes. The objective of this study was to evaluate the prevalence of malnutrition across different age groups in patients with cancer in Brazil and to identify associations with nutrition impact symptoms (NIS). Methods In this observational, cross-sectional, multicenter study, the authors evaluated 4783 patients with cancer aged >= 20 years who were admitted to 45 public hospitals in Brazil. Nutritional status, nutritional risk, and NIS were evaluated using the Patient-Generated Subjective Global Assessment. Results More than one-fourth (25.5%) of all participants were aged >= 65 years. In patients aged >= 65 years, the prevalence of moderate/suspected and severe malnutrition was 55%, it was 45.4% in those aged 51 to 64 years, and it was 36.1% in those aged = 65 years were no appetite (odds ratio [OR], 1.90; 95% CI, 1.62-2.22; P < .05) and dry mouth (OR, 1.40; 95% CI, 1.1-1.67; P < .05). In patients between ages 51 and 64 years, compared with those aged = 65 years who have cancer. The occurrence of NIS was higher in the population aged >50 years than in those aged