Attenuation correction in SPECT based on transmission studies and Monte Carlo simulations of build-up functions.

Attenuation correction in SPECT based on transmission studies and Monte Carlo simulations of build-up functions.
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基于传输研究和构建函数的蒙特卡罗模拟的 SPECT 衰减校正。

DOI:
--
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发表时间:
1990
影响因子:
9.3
通讯作者:
Sven
Sven
中科院分区:
医学1区
文献类型:
--
作者:
M. Ljungberg;Sven

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由于光子的衰减和物体中散射光子的贡献,SPECT图像中的定量信息被扭曲。因此,为了能够进行适当的衰减校正,了解不同衰减组织的分布是很重要的。提出了一种基于密度图和累积函数每次校正一个像素的校正方法。密度图是通过使用安装在闪烁摄像机头上的外部固体57Co洪水源对物体进行透射测量而产生的。物体的轮廓是由地图精确定义的,因为物体外部的密度值非常接近于零。散射在物体中的光子的积累已经用蒙特卡洛代码模拟出来了。用99mTc、201T1和111In线源在非均匀Alderson幻体的不同部位进行了spect研究。利用测量的密度图和模拟的累积函数对发射图像进行了光子衰减校正。结果表明,采用上述衰减校正方法,对不同放射性核素在非均匀区放射性的定量测量精度可达+/- 10%以内。
The quantitative information in SPECT images is distorted by photon attenuation and contribution of photons scattered in the object. It is, therefore, important to know the distribution of different attenuating tissues in order to be able to perform a proper attenuation correction. A correction method, based on correcting one pixel at a time by using density maps and build-up functions, has been developed. The density map has been produced by transmission measurements of the object using an external, solid 57Co flood source mounted on the scintillation camera head. The outline of the object is accurately defined by the map since the density values outside the object are very close to zero. The build-up of photons scattered in the object has been simulated by a Monte-Carlo code. SPECT-studies with 99mTc, 201T1 and 111In line sources in different parts of a non homogeneous Alderson phantom have been performed. The emission images have been corrected for photon attenuation using the measured density maps and the simulated build-up functions. The results show that quantitative measurements of the radioactivity in nonhomogeneous area can be accomplished to within +/- 10% for different radionuclides by using the attenuation correction described.
SPECT 中的非各向同性衰减:定量效应和补偿技术的模型测试。
DOI: --
发表时间: 1987
期刊: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子: --
作者:
Manglos,SH;Jaszczak,RJ;Floyd,CE;Hahn,LJ;Greer,KL;Coleman,RE
通讯作者: Coleman,RE
DOI: --
发表时间: 1989-04
期刊: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子: --
作者:
Benjamin M. W. Tsui;G. T. Gullberg;E. Edgerton;J. Ballard;J. Perry;W. H. McCartney;J. Berg
通讯作者: Benjamin M. W. Tsui;G. T. Gullberg;E. Edgerton;J. Ballard;J. Perry;W. H. McCartney;J. Berg