The importance of watching our weights: how the choice of weights for non-independent sib pairs can dramatically alter results.
The importance of watching our weights: how the choice of weights for non-independent sib pairs can dramatically alter results.
复制标题
观察权重的重要性：非独立同胞对权重的选择如何显着改变结果。
DOI：
10.1002/gepi.1370170763
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Blacker,D
中科院分区：
文献类型：
--
作者：
VanEerdewegh,P;Dupuis,J;Santangelo,SL;Hayward,LB;Blacker,D
Handling non‐independent sib pairs in families with multiple affected sibs presents a problem in likelihood‐based nonparametric linkage analyses. We contrast the more stable partial‐likelihood solution in MAPMAKER/SIBS with the extremely variable partial‐likelihood approach used in ASPEX, and the potential inflation of lods when the problem is ignored as in BETA.
