Persistent Symptoms and Objectively Measured Balance Performance Among OEF/OIF Veterans With Remote Mild Traumatic Brain Injury
Persistent Symptoms and Objectively Measured Balance Performance Among OEF/OIF Veterans With Remote Mild Traumatic Brain Injury
复制标题
DOI：
10.1097/htr.0000000000000385
复制
发表时间：
2018-11-01
影响因子：
2.4
通讯作者：
Brenner, Lisa A.
中科院分区：
文献类型：
--
作者：
Hebert, Jeffrey R.;Forster, Jeri E.;Brenner, Lisa A.
目的：研究头晕、疲劳和抑郁与创伤后应激障碍（PTSD）之间的线性关系，并客观测量患有远程轻度创伤性脑损伤（mTBI）的退伍军人的平衡表现。设置：学术实验室;退伍军人事务医疗中心。参与者：30名在伊拉克/阿富汗服役的退伍军人（28名男性），其最近的mTBI持续超过6个月。设计：横断面观察性试验。主要测量方法：计算机动态姿势-感觉组织测试（CDP-SOT）和社区平衡和流动性（CB&M）量表测量平衡。头晕（头晕障碍量表），疲劳（改良疲劳影响量表），抑郁相关症状（贝克抑郁量表-II），和PTSD相关症状（PTSD检查表5）也measured.Results：客观测量的平衡，CDP-SOT复合，受损（平均得分为67.9）。CDP-SOT评分与头晕（r = -0.53; P = 0.002）、疲劳（r = -0.38; P = 0.03）、抑郁（r = -0.55; P = 0.001）和PTSD症状（r = -0.53; P = 0.002）相关。头晕、距最近mTBI的时间、PTSD症状和抑郁综合解释了CDP-SOT评分的显著变异性（R-2 = 0.46; P = 0.003），疲劳抑郁和PTSD症状也是如此（R-2 = 0.33; P = 0.01）。研究结果表明，头晕、疲劳、抑郁和创伤后应激障碍以及自最近一次mTBI以来的时间可能会影响平衡表现。需要进一步的研究来确定这些共同发生的症状的潜在相互关联的自然历史。
Objective: To investigate linear relationships between dizziness, fatigue, and depression and posttraumatic stress disorder (PTSD) and objectively measured balance performance in Veterans with remote mild traumatic brain injury (mTBI).Setting: Academic laboratory; Veterans Affairs Medical Center.Participants: Thirty Veterans (28 men) who served in Iraq/Afghanistan and whose most recent mTBI was sustained more than 6 months prior to enrollment.Design: Cross-sectional, observational trial.Main Measures: The Computerized Dynamic Posturography-Sensory Organization Test (CDP-SOT) and the Community Balance and Mobility (CB&M) scale measured balance. Dizziness (Dizziness Handicap Inventory), fatigue (Modified Fatigue Impact Scale), depression-related symptoms (Beck Depression Inventory-II), and PTSD-related symptoms (PTSD Checklist 5) were also measured.Results: Objectively measured balance, CDP-SOT composite, was impaired (mean score of 67.9). CDP-SOT scores correlated with dizziness (r = -0.53; P = .002), fatigue (r = -0.38; P = .03), depression (r = -0.55; P = .001), and PTSD symptoms (r = -0.53; P = .002). Dizziness, time since most recent mTBI, and PTSD symptoms and depression combined explained significant variability in CDP-SOT scores (R-2 = 0.46; P = .003), as did fatigue depression and PTSD symptoms (R-2 = 0.33; P = .01).Conclusions: Impaired balance was identified among the cohort. Findings suggest that dizziness, fatigue, depression and PTSD, and time since most recent mTBI may influence balance performance. Additional research is needed to identify the potentially interrelated natural histories of these co-occurring symptoms.