Adaptive response of hypertrophied skeletal muscle to endurance training.
Adaptive response of hypertrophied skeletal muscle to endurance training.
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肥大的骨骼肌对耐力训练的适应性反应。
DOI：
10.1152/jappl.1985.59.1.127
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发表时间：
1985
影响因子：
3.3
通讯作者：
P. D. Gollnick
中科院分区：
文献类型：
--
作者：
M. Riedy;R. L. Moore;P. D. Gollnick
研究了大鼠肥大的比目鱼肌和跖肌对耐力训练的反应。肥大是通过双侧腓肠肌的切除而产生的。腓肠肌切除后 30 天开始进行为期 13 周的跑步训练计划，加剧了肌肥大（P 小于 0.01）。久坐大鼠增大的肌肉的琥珀酸脱氢酶活性与正常动物相似，训练后的增加也是如此。磷酸化酶和己糖激酶活性未因实验扰动而改变。耐力训练动物的肝脏、比目鱼肌和跖肌在运动过程中糖原消耗率较低（P 小于 0.01）。久坐组或训练组中正常肌肉和肥大肌肉的糖原消耗率没有差异。这些数据表明，广泛肥大的肌肉对训练和锻炼的反应与正常肌肉相似。
The response of hypertrophied soleus and plantaris muscle of rats to endurance training was studied. Hypertrophy was produced by bilateral extirpation of the gastrocnemius muscle. A 13-wk training program of treadmill running initiated 30 days after removal of the gastrocnemius muscle accentuated (P less than 0.01) the hypertrophy. Succinate dehydrogenase activities of the enlarged muscles of sedentary rats were similar to those of normal animals, as were the increases associated with training. Phosphorylase and hexokinase activities were unaltered as a result of the experimental perturbations. Rates of glycogen depletion during exercise were lower (P less than 0.01) in the liver and soleus and plantaris muscles of endurance-trained animals. No difference existed in the rate of glycogen depletion of normal and hypertrophied muscle within the sedentary or trained groups. These data demonstrate that extensively hypertrophied muscle responds to training and exercise in a manner similar to that of normal muscle.