Electrochemical Cross-Dehydrogenative Coupling of N-Aryl-tetrahydroisoquinolines with Phosphites and Indole

Electrochemical Cross-Dehydrogenative Coupling of N-Aryl-tetrahydroisoquinolines with Phosphites and Indole
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DOI:
10.1002/ejoc.201801883
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发表时间:
2019-04-16
影响因子:
2.8
通讯作者:
Xiang, Jinbao
Xiang, Jinbao
中科院分区:
化学3区
文献类型:
--
作者:
Xie, Wenxia;Liu, Nian;Xiang, Jinbao

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研究了N-芳基四氢异喹啉与亚磷酸酯和吲哚的无金属无试剂电化学交叉偶联反应。该方法提供了一种环境友好且简单的方法,用于以中等至高产率构建C-P和C-C键,并且具有宽的官能团耐受性。
A metal- and reagent-free, electrochemical cross-dehydrogenative coupling reaction of N-aryl-tetrahydroisoquinolines with phosphites and indole is developed. This method provides an environmentally benign and simple approach for the construction of C-P and C-C bonds in moderate to high yields with wide tolerance of functional groups.