Lipase catalysed Michael addition of secondary amines to acrylonitrile.
Lipase catalysed Michael addition of secondary amines to acrylonitrile.
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DOI：
10.1039/b402244k
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发表时间：
2004-07
影响因子：
4.9
通讯作者：
Oliver Torre;I. Alfonso;V. Gotor
中科院分区：
文献类型：
--
作者：
Oliver Torre;I. Alfonso;V. Gotor
描述了一种新的酶促方法。来自南极假丝酵母的脂肪酶B的不同制备物能够催化仲胺与丙烯腈的Michael型加成。这一新的反应拓宽了这些生物催化剂在有机合成中的应用。
A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.