Cross-frequency interactions between frontal theta and posterior alpha control mechanisms foster working memory
Cross-frequency interactions between frontal theta and posterior alpha control mechanisms foster working memory
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DOI：
10.1016/j.neuroimage.2018.07.067
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发表时间：
2018-11-01
期刊：
影响因子：
5.7
通讯作者：
Miller, Gregory A.
中科院分区：
文献类型：
--
作者：
Popov, Tzvetan;Popova, Petia;Miller, Gregory A.
在theta（4-8 Hz）和alpha（8-14 Hz）频带中的神经振荡活动与执行功能的实现相关，其中中线额叶皮层中的theta和后顶叶皮层中的alpha与工作记忆（WM）负荷相关。为了确定这些空间和光谱上不同的神经现象如何在WM服务中组织的大规模额顶叶网络内相互作用，当受试者执行N-back WM任务时记录EEG。额叶θ功率增加，由后部α减少，跟踪参与者的成功WM性能。这些功率波动呈负相关的试验和预测的反应时间，这表明功能上重要的沟通渠道内的额顶叶网络。格兰杰因果关系分析显示，直接顶叶通过阿尔法和额叶顶叶通过θ沟通。结果鼓励考虑这些双向的，功率到功率，交叉频率控制机制作为支持执行功能的大脑网络组织的一个重要特征。
Neural oscillatory activity in the theta (4-8 Hz) and alpha (8-14 Hz) bands has been associated with the implementation of executive function, with theta in midline frontal cortex and alpha in posterior parietal cortex related to working memory (WM) load. To identify how these spatially and spectrally distinct neural phenomena interact within a large-scale fronto-parietal network organized in service of WM, EEG was recorded while subjects performed an N-back WM task. Frontal theta power increase, paralleled by posterior alpha decrease, tracked participants' successful WM performance. These power fluctuations were inversely related both across and within trials and predicted reaction time, suggesting a functionally important communication channel within the fronto-parietal network. Granger causality analysis revealed directed parietal to frontal communication via alpha and frontal to parietal communication via theta. Results encourage consideration of these bidirectional, power-to-power, cross-frequency control mechanisms as an important feature of cerebral network organization supporting executive function.