Evaluation of the effect and profitability of gene-assisted selection in pig breeding system
Evaluation of the effect and profitability of gene-assisted selection in pig breeding system
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DOI：
10.1631/jzus.2007.b0822
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发表时间：
2007-10-01
影响因子：
5.1
通讯作者：
Chen Yao-sheng
中科院分区：
文献类型：
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作者：
Li Ya-lan;Zhang Qin;Chen Yao-sheng
目的：评价数量性状基因座（QTL）连锁的直接标记（DR标记）在基因辅助选择（GAS）中的应用效果和效益。方法：随机模拟3个具有分离QTL的群体（100、200、300头母猪，每组10头公猪）。调查了5个经济性状，包括活产数（NBA）、100 kg体重平均日增重（ADG）、饲料转化率（FCR）、100 kg体重背脂（BF）和肌内脂肪（IMF）。选择基于每个性状的估计育种值（EBV）。QTL的有利等位基因起始频率分别为0.1、0.3和0.5。采用基因流法计算经济效益。结果：应用DR标记对5个性状进行遗传选择，选择效率均大于100%。NBA的选择效率最高，ADG的选择效率最低，ADG的QTL方差最小。混合模式应用DR标记，获得了较高的额外遗传增益和额外经济收益。我们还发现，QTL的有利等位基因频率越低，获得的额外回报越高。结论：GAS是提高猪育种遗传增益和经济效益的有效选择方案。
Objective: To evaluate the effect and profitability of using the quantitative trait loci (QTL)-linked direct marker (DR marker) in gene-assisted selection (GAS). Methods: Three populations (100, 200, or 300 sows plus 10 boars within each group) with segregating QTL were simulated stochastically. Five economic traits were investigated, including number of born alive (NBA), average daily gain to 100 kg body weight (ADG), feed conversion ratio (FCR), back fat at 100 kg body weight (BF) and intramuscular fat (IMF). Selection was based on the estimated breeding value (EBV) of each trait. The starting frequencies of the QTL's favorable allele were 0.1, 0.3 and 0.5, respectively. The economic return was calculated by gene flow method. Results: The selection efficiency was higher than 100% when DR markers were used in GAS for 5 traits. The selection efficiency for NBA was the highest, and the lowest was for ADG whose QTL had the lowest variance. The mixed model applied DR markers and obtained higher extra genetic gain and extra economic returns. We also found that the lower the frequency of the favorable allele of the QTL, the higher the extra return obtained. Conclusion: GAS is an effective selection scheme to increase the genetic gain and the economic returns in pig breeding.