Differential Influences of Emotion, Task, and Novelty on Brain Regions Underlying the Processing of Speech Melody
Differential Influences of Emotion, Task, and Novelty on Brain Regions Underlying the Processing of Speech Melody
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DOI：
10.1162/jocn.2009.21099
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发表时间：
2009-07-01
影响因子：
3.2
通讯作者：
Wildgruber, Dirk
中科院分区：
文献类型：
--
作者：
Ethofer, Thomas;Kreifelts, Benjamin;Wildgruber, Dirk
我们研究了涉及在处理语音旋律的大脑区域的功能特性，提出了中性或愤怒的韵律在功能磁共振成像实验中使用析因习惯化设计的话。受试者判断这些声音刺激的情感韵律或词类，可以听到第一，第二或第三次。对声音敏感的颞叶皮层，以及杏仁核、杏仁核和丘脑中背核，对愤怒的反应比对中性韵律的反应更强烈。这些刺激驱动的效应不受任务的影响，这表明这些大脑结构在处理声音中的情感信息时自动参与，并且相对独立于认知需求而运作。相比之下，右颞中回和双侧眶额皮质（OFC）的反应更强的情绪比词分类，但也敏感的愤怒所表达的声音，这表明韵律的一些感知方面也编码在这些地区subserving明确的处理声乐情感。双边OFC表现出选择性调制的情绪和重复，特别是明显的反应，愤怒的韵律，在第一次演示，表明关键作用的OFC在检测的声音信息，这是新颖的和行为相关的。这些结果收敛与以前的研究结果获得的愤怒的面孔，并建议一般参与的眶额皮层识别愤怒的感觉方式无关。综上所述，我们的研究表明，不同方面的声音刺激和知觉需求调节不同的领域参与处理的情绪韵律。
We investigated the functional characteristics of brain regions implicated in processing of speech melody by presenting words spoken in either neutral or angry prosody during a functional magnetic resonance imaging experiment using a factorial habituation design. Subjects judged either affective prosody or word class for these vocal stimuli, which could be heard for either the first, second, or third time. Voice-sensitive temporal cortices, as well as the amygdala, insula, and mediodorsal thalami, reacted stronger to angry than to neutral prosody. These stimulus-driven effects were not influenced by the task, suggesting that these brain structures are automatically engaged during processing of emotional information in the voice and operate relatively independent of cognitive demands. By contrast, the right middle temporal gyrus and the bilateral orbito-frontal cortices (OFC) responded stronger during emotion than word classification, but were also sensitive to anger expressed by the voices, suggesting that some perceptual aspects of prosody are also encoded within these regions subserving explicit processing of vocal emotion. The bilateral OFC showed a selective modulation by emotion and repetition, with particularly pronounced responses to angry prosody during the first presentation only, indicating a critical role of the OFC in detection of vocal information that is both novel and behaviorally relevant. These results converge with previous findings obtained for angry faces and suggest a general involvement of the OFC for recognition of anger irrespective of the sensory modality. Taken together, our study reveals that different aspects of voice stimuli and perceptual demands modulate distinct areas involved in the processing of emotional prosody.