Primary intramedullary spinal cord tumour in pregnancy: a case report.
Primary intramedullary spinal cord tumour in pregnancy: a case report.
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妊娠期原发性脊髓髓内肿瘤：一例报告。
DOI：
10.1038/s41394-018-0059-6
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Y.Yoshida
中科院分区：
文献类型：
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作者：
K.Fujii;M.Orisaka;M.Yamamoto;K.Nishijima;Y.Yoshida
原发性脊髓肿瘤可导致严重的神经系统并发症，甚至死亡。孕妇经常抱怨下肢不适，这通常是由坐骨神经痛引起的。在这里，我们提出的情况下，孕妇，谁最初被认为是坐骨神经痛，但最终被诊断为原发性髓内脊髓tumor.Case presentationA 28岁的孕妇提出了我们的医院与莫名其妙的麻木，她的下肢。她最初被认为是坐骨神经痛，但急性恶化的神经症状和普通磁共振成像（MRI）结果表明恶性肿瘤。患者最终被诊断为C3-Th 5区域的原发性髓内脊髓肿瘤。进行紧急剖腹产，之后使用对比增强MRI、2-脱氧-2-[氟-18]氟-d-葡萄糖正电子发射断层扫描结合计算机断层扫描和脊髓血管造影评价脊髓病变，并开始进一步治疗。然而，虽然病人的脊髓肿瘤手术是在产后早期进行的，她的截瘫和膀胱和直肠的干扰保持不变，甚至1年后surgical.DiscussionBecause的发病率较低的脊髓肿瘤在怀孕期间，没有明确的报告已发表在治疗怀孕的脊髓肿瘤患者。虽然妊娠期间安全的影像学检查有限，但应尽早对此类患者进行干预，以避免不可逆的神经系统恶化。
IntroductionPrimary spinal cord tumours can lead to severe neurological complications and even death. Pregnant women often complain of discomfort of the lower limbs, which is usually caused by sciatica. Here we present the case of a pregnant woman, who was initially considered to have sciatica, but was finally diagnosed with a primary intramedullary spinal cord tumour.Case presentationA 28-year-old pregnant woman presented to our hospital with inexplicable numbness in her lower limbs. She was initially considered to have sciatica, but acute deterioration of neurological symptoms and plain magnetic resonance imaging (MRI) findings suggested malignancy. The patient was finally diagnosed with a primary intramedullary spinal cord tumour at the C3–Th5 region. An emergency caesarean section was performed, after which the spinal cord lesion was evaluated using contrast-enhanced MRI, positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-d-glucose integrated with computed tomography, and spinal angiography, and further treatment was initiated. However, while the patient’s spinal cord tumour surgery was performed in early postpartum, her paraplegia and bladder and rectal disturbances remained unchanged even 1 year after surgery.DiscussionBecause of the low incidence of spinal cord tumours during pregnancy, no definite reports have been published on the treatment of pregnant patients with spinal cord tumours. Although safe imaging tests during pregnancy are limited, intervention in such patients should be performed as early as possible to avoid irreversible neurological deterioration.