Organization of the rostral thalamus in the rat: Evidence for connections to layer I of visual cortex
Organization of the rostral thalamus in the rat: Evidence for connections to layer I of visual cortex
复制标题
大鼠丘脑头端的组织：与视觉皮层 I 层连接的证据
DOI：
10.1002/cne.902340202
复制
发表时间：
1985
影响因子：
2.5
通讯作者：
R. G. Carey
中科院分区：
文献类型：
--
作者：
R. Rieck;R. G. Carey
本研究证明了丘脑皮层投射系统的组织，该系统终止于蒙面大鼠视觉皮层的第一层内。仅限于 I 层的辣根过氧化物酶 (HRP) 注射导致位于腹内侧 (VM) 核和腹侧前外侧核 (VAL) 背内侧亚基内的大中型多极和梭形神经元的逆行标记。注射后，逆行细胞标记也会发生在前内侧核 (AM) 内。将 HRP 注射限制在 I 层后，在经典定义的层内系统（即中央内侧核、旁中央核和中央外侧核）的神经元内，或在层内系统的头端延续部内，未发现过氧化物酶标记。由于 VM、背内侧 VAL 和 AM 核团直接邻近内髓层的部分，因此我们将这种投射到 I 层的丘脑嘴核混合体称为“旁层”系统。我们还提供了细胞结构标准，可用于区分 VAL 复合体内的三个独立的细分，包括 VAL 的“平行层”系统的一部分。相比之下，当将 WGA-HRP 的对照注射置于视觉皮层的细胞颗粒上层或颗粒下层内时，VM、VAL 或 AM 内没有明显数量的神经元被标记。
The present study demonstrates the organization of a thalamocortical projecting system which terminates within layer I of the visual cortex in the hooded rat. Horseradish peroxidase (HRP) injections restricted to layer I resulted in retrograde labeling of large and medium‐sized multipolar and fusiform neurons that are located within the ventromedial (VM) nucleus and a dorsomedial subunit of the ventral anterolateral nucleus (VAL). Retrograde cellular labeling also occurs within the anteromedial nucleus (AM) following these injections. After restriction of HRP injections to layer I, peroxidase labeling was not found within neurons of the classically defined intralaminar system, i.e., central medial, paracentral, and central lateral nuclei, or within the rostral continuations of the intralaminar system. Since the VM, dorsomedial VAL, and AM nuclei are directly adjacent to portions of the internal medullary lamina, we refer to this amalgam of rostral thalamic nuclei that project to layer I as the “paralaminar” system. We also provide cytoarchitectonic criteria that can be used to distinguish three separate subdivisions within the VAL complex, including that portion of the VAL which is part of the “paralaminar” system. In contrast, when control injections of WGA‐HRP are placed within either the cellular supragranular or infragranular layers of the visual cortex, no appreciable number of neurons are labeled within the VM, VAL, or AM.