Human adipose-derived stem cell fiber for breast reconstruction
Human adipose-derived stem cell fiber for breast reconstruction
复制标题
用于乳房重建的人类脂肪干细胞纤维
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
S. Takeuchi
中科院分区：
文献类型：
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作者：
A. Hsiao;T. Okitsu;S. Takeuchi
本文描述了人脂肪源性干细胞（ADSC）纤维的构建和分化为用于乳房重建的脂肪细胞系。采用细胞纤维技术[1]将人ADSCs包埋在水凝胶核壳纤维核心区，诱导成脂分化，维持2个月以上。诱导成脂后，细胞内可见明显大小的脂滴积聚，活力测定显示大部分细胞存活。这些发现表明，使用ADSC纤维是一种很有前途的乳房重建方法。
This paper describes the construction and differentiation of human adipose-derived stem cell (ADSC) fibers into the adipocyte lineage for breast reconstruction. Human ADSCs were encapsulated into the core region of hydrogel core-shell fibers by the cell fiber technology [1], induced for adipogenic differentiation, and maintained for over 2 months. After adipogenic induction, accumulation of lipid droplets of significant size was observed in the cells, and viability assay showed that most of the cells were alive. These findings suggest the use of ADSC fibers as a promising approach for breast reconstruction.
影响因子：
3.3
作者：
Pantoja, Carlos;Huff, Jason T.;Yamamoto, Keith R.
通讯作者：
Yamamoto, Keith R.