NEURAL PROCESSES OF ATTENTIONAL INHIBITION OF RETURN TRACED WITH MAGNETOENCEPHALOGRAPHY
NEURAL PROCESSES OF ATTENTIONAL INHIBITION OF RETURN TRACED WITH MAGNETOENCEPHALOGRAPHY
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DOI：
10.1016/j.neuroscience.2008.07.064
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发表时间：
2008-10-15
期刊：
影响因子：
3.3
通讯作者：
Kakigi, R.
中科院分区：
文献类型：
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作者：
Ayabe, T.;Ishizu, T.;Kakigi, R.
返回抑制（IOR）是指当线索和目标之间的间隔延长时，对空间线索目标的反应时长于对非线索目标的反应时的现象。虽然许多研究已经检查IOR，尚未达成共识的神经机制负责它。我们使用脑磁图（MEG）和测量人类的神经反应的时间过程中的1011，应用一个典型的空间线索范式。线索-目标间隔为600 +/- 200 ms。采用三种实验条件。提示：提示和目标出现在同一位置。无提示;两个刺激出现在相反的位置。中性;提示刺激呈现双侧性。我们发现在后颞区和双侧颞区的信号幅度的差异，并在中央区域之间的线索和uncooked条件的峰值laveling。这些信号分别位于纹外皮质、双侧颞顶交界区（TPJ）和初级运动皮质。双边TPJ活动与识别在感官环境中的显着事件的内部和独立的当前的行为背景下，并可能发挥重要作用，在IOR除了纹外和初级运动皮层。(C)2008年IBRO。由爱思唯尔有限公司出版。保留所有权利。
Inhibition of return (IOR) is a phenomenon that involves reaction times (RTs) to a spatially cued target that are longer than RTs to an uncued target when the interval between the cue and target is prolonged. Although numerous studies have examined IOR, no consensus has yet been reached regarding the neural mechanisms responsible for it. We used magnetoencephalography (MEG) and measured the human neural responses underlying the time course of 1011, applying a typical spatial cueing paradigm. The cue-target interval was 600 +/- 200 ms. Three experimental conditions were employed. Cued; the cue and target were presented at the same location. Uncued; the two stimuli were presented at opposite locations. Neutral; the cue stimulus was presented bilaterally. We found differences in the amplitudes of signals in the postero-temporal and bilateral temporal areas, and peak latencies in a central area between the cued and uncued conditions. These signals were localized to the extrastriate cortex, bilateral temporal-parietal junction (TPJ), and primary motor cortex, respectively. Bilateral TPJ activities are related to the identification of salient events in the sensory environment both within and independent of the current behavioral context and may play an important role in IOR in addition to extrastriate and the primary motor cortex. (C) 2008 IBRO. Published by Elsevier Ltd. All rights reserved.