Analysis of pesticide and veterinary drug residues in baby food by liquid chromatography coupled to Orbitrap high resolution mass spectrometry
Analysis of pesticide and veterinary drug residues in baby food by liquid chromatography coupled to Orbitrap high resolution mass spectrometry
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DOI：
10.1016/j.talanta.2014.07.066
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发表时间：
2015-01-01
期刊：
影响因子：
6.1
通讯作者：
Garrido Frenich, Antonia
中科院分区：
文献类型：
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作者：
Luz Gomez-Perez, Maria;Romero-Gonzalez, Roberto;Garrido Frenich, Antonia
同时测定了几种婴儿食品中的农药和兽药残留，如肉类、鱼类和蔬菜类婴儿食品。采用无净化步骤的通用提取方法。此外，研究了使用代表性基质对所有目标化合物进行适当定量，当使用植物性婴儿食品作为代表性基质时获得了最佳结果，从而可以可靠地定量300多种化合物。该方法得到验证，并获得良好的回收率为大多数化合物的浓度高于50 μ g kg（-1）。检测限（LOD）范围为0.5至50 μ g kg（-1），而定量限（LOQ）确定为10至100 μ g kg（-1）。鉴别限（LOI）范围为0.5至50 μ g kg（-1）。该方法应用于46种不同婴儿食品样本的分析，未发现阳性样本。（C）2014 Elsevier B. V.保留所有权利。
Pesticide and veterinary drug residues have been simultaneously determined in several baby foods as meat, fish and vegetable-based baby food. A generic extraction method without clean-up step was applied. Moreover, the use of a representative matrix for proper quantification of all target compounds was studied and the best results were obtained when vegetable-based baby food was used as representative matrix, allowing the reliable quantification of more than 300 compounds. The method was validated and good recoveries were obtained for most of compounds at concentrations higher than 50 mu g kg(-1). Limits of detection (LOD) ranged from 0.5 to 50 mu g kg(-1), whereas limits of quantification (LOQ) were established between 10 and 100 mu g kg(-1). Limits of identification (LOIs) ranged from 0.5 to 50 mu g kg(-1). This method was applied to the analysis of 46 different baby food samples and no positive samples were found. (C) 2014 Elsevier B.V. All rights reserved.