Effects of thioridazine and withdrawal dyskinesias on workshop performance of mentally retarded young adults.
Effects of thioridazine and withdrawal dyskinesias on workshop performance of mentally retarded young adults.
复制标题
硫利达嗪和戒断运动障碍对弱智年轻人的车间表现的影响。
DOI：
10.1176/ajp.139.11.1447
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Ferguson,DG
中科院分区：
文献类型：
--
作者：
Breuning,SE;Davis,VJ;Matson,JL;Ferguson,DG
作者进行了一项关于硫利达嗪和戒断性运动障碍对弱智青年工作坊表现的影响的两部分研究。在第1部分中，80名智力迟钝的受试者被分为5组，每组16人，根据管理，停药，或非管理硫利达嗪。主要发现是硫利达嗪会损害弱智者的车间表现。在第2部分中，28例受试者被分为4个匹配组，每组7例受试者，他们突然或逐渐停用硫利达嗪，并且他们有或没有戒断性运动障碍。工作坊的表现随着运动障碍的发作而下降，并随着运动障碍的消退而改善。
The authors conducted a two-part study of the effects of thioridazine and withdrawal dyskinesias on the workshop performance of mentally retarded young adults. In part 1, 80 mentally retarded subjects were divided into five groups of 16 according to administration, discontinuation, or nonadministration of thioridazine. The major finding was that thioridazine can impair the workshop performance of mentally retarded individuals. In part 2, 28 subjects were divided into four matched groups of 7 subjects each whose thioridazine dose was abruptly or gradually discontinued and who did or did not have withdrawal dyskinesias. Workshop performance declined with the onset of the dyskinesias and improved as the dyskinesias subsided.