Voluntary ethanol consumption in the absence of hunger and thirst drives
Voluntary ethanol consumption in the absence of hunger and thirst drives
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在没有饥饿和口渴驱动的情况下自愿消耗乙醇
作者：
H. Iso
在水和乙醇之间的选择情况下，对Wistar大鼠的自愿乙醇消耗进行了研究。在持续5天的每个会话中，在2.5至45%（v/v）的五种不同浓度的乙醇和水被给予作为FR-30在12小时的光照和12小时的黑暗期间与食物可用的压力响应的抑制剂。结果表明，大鼠喜欢2.5-5%的乙醇比水，但水比30或45%的乙醇。每日每公斤体重的净乙醇消耗量作为其浓度的函数单调增加，在45%时达到平均值9.08 g/kg。在黑暗时期，大鼠饮用了大部分乙醇和水，尽管当时摄入了大量乙醇。
Voluntary ethanol consumption in Wistar rats was examined in a choice situation between water and ethanol. In each session continuing over 5 days, ethanol at five different concentrations from 2.5 to 45% (v/v) and water were given as reinforcers for FR-30 lever-press responses during 12-h light and 12-h dark periods with food available. The results indicated that rats preferred 2.5–5% ethanol to water, but water to 30 or 45% ethanol. Daily net ethanol consumption per kg body weight increased monotonically as a function of its concentration and reached a mean value of 9.08 g/kg at 45%. Rats drank most of the ethanol and water during the dark period, despite the large amount of ethanol intake occurring at that time.