Circadian Rhythm and the Seasonal Variation in Childhood Febrile Seizure
Circadian Rhythm and the Seasonal Variation in Childhood Febrile Seizure
复制标题
昼夜节律和儿童热性惊厥的季节变化
DOI：
10.22037/ijcn.v11i3.10865
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发表时间：
2017
影响因子：
0.8
通讯作者：
V. Aminzadeh
中科院分区：
文献类型：
--
作者：
R. Sharafi;Afagh Hassanzadeh Rad;V. Aminzadeh
目的探讨小儿热性惊厥（FS）的昼夜节律和季节变化。材料与方法本研究采用回顾性横断面研究方法，对住院患者的病历资料进行分析。研究者评估了2010年1月至2013年1月期间转诊至伊朗北方拉什特17-Shahrivar医院急诊科的6至60个月的单纯FS患者的记录。通过检查表收集数据，包括年龄、性别、体温、癫痫发作持续时间、季节、月份、昼夜变化和意识水平。结果349例患者中，男193例（55.3%），女156例（44.7%），平均年龄（22.85±18.34）月。患者平均体温为38.45±0.53°C。平均发作持续时间为97.91±57秒。清醒170例（48.7%），困倦33例（9.5%），睡眠146例（41.8%）。冬季118例（33.8%）、下午132例（37.8%）、1月55例（15.8%）。结论下丘脑对体温的调节受昼夜节律的影响。FS是儿童期最常见的癫痫发作形式，由多因素引起。另外，癫痫患者癫痫发作的发生可能受到昼夜节律的影响。癫痫发作在一天中24小时内的特定时间发生得更频繁。
Objective We aimed to assess the circadian rhythm and the seasonal variation in childhood febrile seizure (FS). Materials & Methods This descriptive cross-sectional study was conducted retrospectively on patients’ records. Investigators assessed the records of patients with simple FS aged 6 to 60 months referred to Emergency Department of 17-Shahrivar Hospital, Rasht northern Iran during Jan 2010 to Jan 2013. Data were gathered by a checklist including age, sex, temperature, duration of seizure, seasonal, months, diurnal variation, and level of consciousness. Results Totally, 349 patients including 193 (55.3%) boys and 156 (44.7%) girls with the mean age of 22.85±18.34 months were enrolled in this study. The mean temperature of patients was 38.45±0.53°C. The mean duration of seizure was 97.91±57 sec. Awake, drowsy and slept patients were noted in 170 (48.7%), 33(9.5%) and 146 (41.8%) cases, respectively. Most of the FS occurred in winter 118 (33.8%), afternoon 132 (37.8%) and in Jan 55 (15.8%). Conclusion Body temperature adjusted by hypothalamus affecting by circadian rhythm. FS is the most common form of seizure in childhood occurred by multifactorial issues. Otherwise, the occurrence of seizure in patients with epilepsy may be affected by the circadian rhythm. Seizures happen more frequent at a specific time in 24 h during a day.