Hydrogenolysis of 2-tosyloxy-1,3-propanediol into 1,3-propanediol over Raney Ni catalyst
Hydrogenolysis of 2-tosyloxy-1,3-propanediol into 1,3-propanediol over Raney Ni catalyst
复制标题
雷尼镍催化剂上2-甲苯磺酰氧基-1,3-丙二醇氢解成1,3-丙二醇
DOI：
10.5935/0103-5053.20130049
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发表时间：
2013
影响因子：
1.4
通讯作者：
Ji Jianbing
中科院分区：
文献类型：
--
作者：
Zhi;Jianli Wang;Zhe Lu;M. Luo;Miao Zhang;Lixin Xu;Ji Jianbing
2-甲苯磺酰氧基-1,3-丙二醇 (TPD) 是生产 1,3-丙二醇 (1,3-PD) 的潜在前体，是通过借助保护基技术对甘油进行甲苯磺酰化来生产的。在这项工作中，讨论了在雷尼镍催化剂上TPD氢解成1,3-PD的不同反应参数，以优化选择性形成1,3-PD的反应条件。 TPD的氢解机制和副反应也通过气相色谱-质谱（GC-MS）技术得到证实。
2-Tosyloxy-1,3-propanediol (TPD), a potential precursor for 1,3-propanediol (1,3-PD) production, is produced by the tosylation of glycerol with the help of protecting group techniques. In this work, the hydrogenolysis of TPD into 1,3-PD over Raney Ni catalyst is discussed at different reaction parameters to optimize the reaction conditions for selective formation of 1,3-PD. The mechanisms of the hydrogenolysis of TPD and the side reactions were also confirmed by gas chromatography-mass spectrometry (GC-MS) technique.