Simplifying the setup for vacuum-outlet GC: using a restriction inside the injection port.
Simplifying the setup for vacuum-outlet GC: using a restriction inside the injection port.
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简化真空出口 GC 的设置：在进样口内使用限制装置。
DOI：
10.1002/jssc.200900009
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发表时间：
2009
影响因子：
3.1
通讯作者：
C. English
中科院分区：
文献类型：
--
作者：
J. de Zeeuw;S. Reese;J. Cochran;S. Grossman;T. Kane;C. English
真空气相色谱的应用与加压气相色谱相比有几个优点。其关键特征之一是最佳气速很高。与宽内径的短毛细管柱相结合，使用标准GC-MS设备可以缩短分析时间。为了使真空GC可以使用GC-MS系统，必须在色谱柱的进样侧设置限制。这种限制通常由失活的0.1 mm内径制成。与分析柱连接的熔融石英管。这种限制将起作用，但在耦合、减少死体积和鲁棒性方面存在实际挑战。一种新的节流方式是将节流器并入进样口。使用内径为0.025 mm的定义明确的熔融石英短片，可以使用Press-Tight型连接器进行限制，并将其定位在注射端口内。通过这样做，限制是非常短的，并在高温下所有的时间。活性起最小的作用，并且泄漏也不会成为问题，因为联轴器处于100%惰性气体中。使用这种概念获得的数据是有希望的，因为真空GC变得更容易和更强大。
The application of vacuum GC has several advantages over pressurized GC. One of the key characteristics is that the optimal gas velocity is very high. Combined with short capillary columns of wide internal diameter, this results in short analysis times using standard GC-MS equipment. To make vacuum GC possible using a GC-MS system, a restriction must be positioned at the injection side of the column. This restriction is usually made of deactivated 0.1 mm i.d. fused-silica tubing which is coupled to the analytical column. Such restrictions will work, but practical challenges are found in coupling, reducing dead volume and robustness. A new way of making restrictions is by incorporating the restriction into the injection port. Using well-defined short pieces of fused silica with internal diameter of 0.025 mm, one can make a restriction using a Press-Tight type connector, and position this inside the injection port. By doing this, the restriction is very short and at high temperature all the time. Activity plays a minimal role, and also leaks will not be an issue as the coupling is in 100% inert gas. Data obtained using this concept is promising as vacuum GC becomes easier and more robust.
串联质谱法用于粗脑提取物中痕量测定色氨酸。
影响因子：
7.4
作者：
Johnson,JV;Yost,RA;Faull,KF
通讯作者：
Faull,KF