GENETIC METHOD FOR DETERMINING ORDER OF EVENTS IN A BIOLOGICAL PATHWAY

GENETIC METHOD FOR DETERMINING ORDER OF EVENTS IN A BIOLOGICAL PATHWAY
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DOI:
10.1073/pnas.70.7.2046
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发表时间:
1973-01-01
影响因子:
11.1
通讯作者:
BOTSTEIN, D
BOTSTEIN, D
中科院分区:
综合性期刊1区
文献类型:
--
作者:
JARVIK, J;BOTSTEIN, D

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我们描述了一种简单的基因测试的应用,它表明了形态发生或生化途径中事件的顺序。这项测试使用了温度敏感(Ts)和冷敏感(Cs)突变体,并对缺陷表达的时间进行了排序。
We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which thetsandcsdefects are expressed.