Periovulatory progesterone concentration in the peripheral plasma of the rhesus monkey with a methodologic note on the detection of ovulation.
Periovulatory progesterone concentration in the peripheral plasma of the rhesus monkey with a methodologic note on the detection of ovulation.
复制标题
恒河猴外周血浆中排卵期黄体酮浓度以及排卵检测的方法学说明。
DOI：
10.1210/endo-82-1-143
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发表时间：
1968
期刊：
影响因子：
4.8
通讯作者：
E. Knobil
中科院分区：
文献类型：
--
作者：
E. Johansson;J. D. Neill;E. Knobil
通过竞争性蛋白结合分析对 23 只正常周期的恒河猴进行外周血浆孕酮浓度测量，并通过连续剖腹手术期间直接观察确定与排卵日的关系。血浆黄体酮浓度在排卵前一天开始突然增加，在排卵后 3-4 天达到约 4 mμg/ml 的最大值。在排卵当天，一些动物的血浆黄体酮浓度下降，其他动物保持不变，其余的则持续增加。描述了一种快速而简单的方法，该方法基于对用于测量黄体酮的竞争性蛋白结合技术的修改，该方法可以高度可靠地确定恒河猴的排卵日。 （内分泌学 82：143，1968）
Peripheral plasma progesterone concentrations were measured by competitive protein binding analysis in 23 normally cycling rhesus monkeys and related to the day of ovulation as established by direct observation during serial laparotomies. Plasma progesterone concentrations began to increase abruptly on the day prior to ovulation, reaching maximal values of approximately 4 mμg/ml 3–4 days after ovulation. On the day of ovulation some animalsshowed a decline in plasma progesterone concentration, others remained unchanged, and the remainder increased in continuous fashion. A rapid and simple method, based on a modification of the competitive protein binding technique for the measurement of progesterone, which permits the highly reliable determination of the day of ovulation in the rhesus monkey is described. (Endocrinology 82: 143, 1968)