Plant-based vaccines against viruses.
Plant-based vaccines against viruses.
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DOI:
10.1186/s12985-014-0205-0
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发表时间:
2014-12-03
期刊:
影响因子:
4.8
通讯作者:
Rybicki EP
中科院分区:
文献类型:
--
作者:
Rybicki EP
Plant-made or “biofarmed” viral vaccines are some of the earliest products of the technology of plant molecular farming, and remain some of the brightest prospects for the success of this field. Proofs of principle and of efficacy exist for many candidate viral veterinary vaccines; the use of plant-made viral antigens and of monoclonal antibodies for therapy of animal and even human viral disease is also well established. This review explores some of the more prominent recent advances in the biofarming of viral vaccines and therapies, including the recent use of ZMapp for Ebolavirus infection, and explores some possible future applications of the technology.
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