[Data of the quantitative orofacial somatosensory functions of healthy subjects and its influence factors analysis].
[Data of the quantitative orofacial somatosensory functions of healthy subjects and its influence factors analysis].
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发表时间：
2015-06
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通讯作者：
Guang-ju Yang;Ye Cao;Lei Zhang;X. Qin;Q. Xie
中科院分区：
文献类型：
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作者：
Guang-ju Yang;Ye Cao;Lei Zhang;X. Qin;Q. Xie
目的通过对健康个体进行标准化的定量感觉测试，建立三叉神经区按性别、年龄组和部位分层的初步体感数据，并评价性别、年龄和部位对体感功能的影响。方法德国神经病理性疼痛研究网络研制的标准化QST电池组由13个不同参数组成。共有70名健康人参加。研究对象按年龄分为两组：青年组(女性16例，男性16例，年龄24~40岁)和老年组(女性20例，男性18例，年龄41~69岁)。这项测试是在双侧的眶下、大脑和手部区域进行的。结果提供了按性别、年龄组和地点分层的初步口腔面部体感数据。在大多数参数上，女性比男性敏感(P<；0.05)。年龄对大多数参数有显著影响(P<；0.05)，青年组对热痛阈值(HPT)的敏感性高于老年组(P<；0.01)：青年组(38.07±2.94)°C，老年组(39.85±3.52)°C，温觉探测阈值(WDT)：青年组(1.40±0.74)°C，老年组(1.89±1.14)°C，机械探测阈值(MDT)：青年组(0.73±1.66)mN，老年组(1.41±2.82)mN；压痛阈值：青年组(171.71±92.5 1)kPa，老年组(196.36±73.73)kPa.冷痛阈值：青年组(2 5.90±5.38)°C，老年组(2 1.6 4±6.78)°C；冷检测阈值：青年组(-0.97±0.5 5)°C，老年组(-1.3 6±0.90)°C；发条比：青年组(3.33±2.2 0)，老年组(2.67±1.6 8)。机械痛觉阈值：青年组(111.50±88.93)mN，老年组(104.49±94.94)mN，机械痛敏感度(MPS)：青年组(6.96±5.61)，老年组(8.93±6.5 3)，振动检测阈值：青年组(7.4 4±0.5 2)分，老年组(7.5 5±0.48)分。躯体感觉功能具有部位依赖性(P<；0.001)，三叉神经眶下和大脑两个部位对CDT、HPT、WDT、热感觉阈值、MDT、MPT、MPS和PPT的敏感性高于手部(P<；0.001)，而VDT则相反(P<；0.001)。结论初步建立了汉族人按性别、年龄、地点分层的口面部体感数据。本研究通过标准化的定量感觉测试来评估性别、年龄和地点对口面部躯体感觉功能的影响。
OBJECTIVE To establish the preliminary somatosensory data stratified by gender, age group, and sites in the trigeminal region through standardized quantitative sensory testing on healthy individuals, and to evaluate the effects of gender, age, and sites on somatosensory functions. METHODS The standardised QST battery developed by the German Research Network on Neuropathic Pain consists totally of 13 different parameters. A total of 70 healthy individuals participated. The subjects were stratified into two groups according to age: younger group (16 female, 16 male, age 24-40 years old) and elder group (20 female, 18 male, age 41-69 years old). The test was performed bilaterally over the infraorbital, mental, and hand regions. RESULTS The preliminary orofacial somatosensory data stratified by gender, age group, and sites were presented. Female were more sensitive than male for most of the parameters (P<0.05). Age had a significant effect on most of the parameters (P<0.05), the younger group was more sensitive compared with the elder group (P<0.01) for heat pain threshold (HPT): younger group (38.07±2.94) °C, elder group (39.85±3.52) °C; warmth detection threshold (WDT): younger group (1.40±0.74) °C, elder group (1.89±1.14) °C; mechanical detection threshold (MDT): younger group (0.73±1.66) mN, elder group (1.41±2.82) mN; pressure pain threshold (PPT): younger group (171.71±92.51) kPa, elder group (196.36±73.73) kPa; cold pain threshold (CPT): younger group (25.90±5.38) °C, elder group (21.64±6.78) °C; cold detection threshold (CDT): younger group (-0.97±0.55) °C, elder group (-1.36±0.90) °C, and wind-up ratio (WUR): younger group (3.33± 2.20), elder group (2.67±1.68). The inverse results were demonstrated for mechanical pain threshold (MPT): younger group (111.50±88.93) mN, elder group (104.49±94.94) mN; mechanical pain sensitivity (MPS): younger group (6.96±5.61), elder group (8.93±6.53), and vibration detection threshold (VDT): younger group (7.44±0.52) scale, elder group (7.55±0.48) scale (P<0.05). Somatosensory function was site dependent (P<0.001), the two trigeminal sites (infraorbital and mental) were more sensitive than the hand for CDT, HPT, WDT, thermal sensory limen (TSL), MDT, MPT, MPS, and PPT (P<0.001), but the inverse result was observed for VDT (P<0.001). CONCLUSION The preliminary orofacial somatosensory data of Han Ethnicity stratified by gender, age group, and sites were established. The study evaluated the effects of gender, age and sites on orofacial somatosensory functions by employment standardized quantitative sensory testing.