MEASURING PET SCANNER SENSITIVITY - RELATING COUNTRATES TO IMAGE SIGNAL-TO-NOISE RATIOS USING NOISE EQUIVALENT COUNTS

MEASURING PET SCANNER SENSITIVITY - RELATING COUNTRATES TO IMAGE SIGNAL-TO-NOISE RATIOS USING NOISE EQUIVALENT COUNTS
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DOI:
10.1109/23.106715
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发表时间:
1990-04-01
影响因子:
1.8
通讯作者:
HOFFMAN, EJ
HOFFMAN, EJ
中科院分区:
工程技术3区
文献类型:
--
作者:
STROTHER, SC;CASEY, ME;HOFFMAN, EJ

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用标准化的直径20厘米的尼龙圆柱体测量了五种不同的CTI/Siemens PET(正电子发射断层扫描)扫描仪的真符合计数(TCC)和噪声等效计数(NEC)曲线,这些扫描仪具有几种扫描仪-准直器组合:(1)831/08-12,准直器间隔为1 mm;(2) 933/08-12和933/08-16具有3 ~ 1mm锥形准直器隔片;(3) 931/08-12具有3至1毫米的锥形和1毫米的准直器隔片,931/08-16具有3至1毫米的锥形准直器隔片。并将933/08-12脑区的TCC和NEC曲线与Alderson脑区进行比较。总的来说,TCC曲线显示的峰值计数率和活性水平比NEC曲线的相应值高出50%。造成这种差异的主要因素是随机分量的噪声效应。研究表明,与奥尔德森脑幻象相比,标准的20厘米圆柱体不能很好地预测PET脑成像的计数率
True coincidence count (TCC) and noise equivalent count (NEC) curves were measured with a standardized 20-cm-diameter nylon cylinder for five different CTI/Siemens PET (positron emission tomography) scanners with several scanner-collimator combinations: (1) 831/08-12 with 1-mm collimator septa; (2) 933/08-12 and 933/08-16 with 3 to 1-mm tapered collimator septa; and (3) 931/08-12 with 3 to 1-mm tapered and a 1-mm collimator septa and the 931/08-16 with 3 to 1-mm tapered collimator septa. In addition, TCC and NEC curves on the 933/08-12 were compared with those from an Alderson brain phantom. In general, it is found that the TCC curves indicated peak count rates and activity levels that were as much as 50% higher than the corresponding values from NEC curves. The primary factor causing this difference is the noise effect of the randoms component. It is demonstrated that, compared to the Alderson brain phantom, the standard 20-cm cylinder is a poor predictor of count rate performance for PET brain imaging.<>