ELASTIC-MODULUS OF HUMAN INTACT LEFT VENTRICLE DETERMINATION AND PHYSIOLOGICAL INTERPRETATION
ELASTIC-MODULUS OF HUMAN INTACT LEFT VENTRICLE DETERMINATION AND PHYSIOLOGICAL INTERPRETATION
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DOI:
10.1007/bf02477722
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发表时间:
1975-01-01
期刊:
影响因子:
--
通讯作者:
SANDLER, H
中科院分区:
文献类型:
--
作者:
GHISTA, DN;VAYO, WH;SANDLER, H
The left ventricle (l.v.) is represented as a shell of muscle whose performance is characterised in terms of the chamber pressure and stress/strain in the ventricular wall; the effective elastic modulus of the l.v. relates these peerformance variables, and hence represents the transfer function of the left ventricular physiological system. A method is presented for indirectly determining the effective modulusEfor the left ventricle. The method employs a thick-walled mathematical model of the l.v. having a homogeneous isotropic medium. Instantaneous values ofEare determined for subjects with heart diseases of varied etiologies, in order to assess the responses of the l.v. to chronic overloads of pressure and volume. Resulting values forEare used diagnostically to characterise the physiological state of the l.v. Normal values ofE, at systole, indicate that the strength of contraction exercised by the l.v. is normal, and hence is an indication of the l.v. having adjusted to the heart disease.