ELASTIC-MODULUS OF HUMAN INTACT LEFT VENTRICLE DETERMINATION AND PHYSIOLOGICAL INTERPRETATION

ELASTIC-MODULUS OF HUMAN INTACT LEFT VENTRICLE DETERMINATION AND PHYSIOLOGICAL INTERPRETATION
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DOI:
10.1007/bf02477722
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发表时间:
1975-01-01
期刊:
MEDICAL & BIOLOGICAL ENGINEERING
影响因子:
--
通讯作者:
SANDLER, H
SANDLER, H
中科院分区:
其他
文献类型:
--
作者:
GHISTA, DN;VAYO, WH;SANDLER, H

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左心室(L.V.)被表示为肌肉的外壳,其性能的特征是室壁中的腔内压力和应力/应变;左心室的有效弹性模数。将这些性能变量联系起来,从而代表了左心室生理系统的传递函数。本文提出了一种间接测定左心室有效弹性系数的方法。该方法采用了L V的厚壁数学模型。具有均匀的各向同性介质的。测定各种病因心脏病受试者的E瞬时值,以评估左心室的反应。压力和体量的慢性过载。E的结果值用于诊断,以表征左心室的生理状态。收缩时E的正常值表示左心室收缩的强度。是正常的,因此是左心室的一个迹象。已经适应了心脏病。
The left ventricle (l.v.) is represented as a shell of muscle whose performance is characterised in terms of the chamber pressure and stress/strain in the ventricular wall; the effective elastic modulus of the l.v. relates these peerformance variables, and hence represents the transfer function of the left ventricular physiological system. A method is presented for indirectly determining the effective modulusEfor the left ventricle. The method employs a thick-walled mathematical model of the l.v. having a homogeneous isotropic medium. Instantaneous values ofEare determined for subjects with heart diseases of varied etiologies, in order to assess the responses of the l.v. to chronic overloads of pressure and volume. Resulting values forEare used diagnostically to characterise the physiological state of the l.v. Normal values ofE, at systole, indicate that the strength of contraction exercised by the l.v. is normal, and hence is an indication of the l.v. having adjusted to the heart disease.