Phase I, pharmacokinetic, and pharmacodynamic study of intravenously administered Ad5CMV-p53, an adenoviral vector containing the wild-type p53 gene, in patients with advanced cancer.
Phase I, pharmacokinetic, and pharmacodynamic study of intravenously administered Ad5CMV-p53, an adenoviral vector containing the wild-type p53 gene, in patients with advanced cancer.
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Ad5CMV-p53(一种含有野生型 p53 基因的腺病毒载体)在晚期癌症患者中静脉注射的 I 期药代动力学和药效学研究。
DOI:
10.1200/jco.2005.03.6756
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发表时间:
2006
期刊:
影响因子:
--
通讯作者:
Eckhardt,SGail
中科院分区:
文献类型:
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作者:
Tolcher,AnthonyW;Hao,Desiree;deBono,Johann;Miller,Alex;Patnaik,Amita;Hammond,LisaA;Smetzer,Leslie;VanWartHood,Jill;Merritt,James;Rowinsky,EricK;Takimoto,Chris;VonHoff,Dan;Eckhardt,SGail