Improved outcome in the treatment of pediatric multifocal Langerhans cell histiocytosis
Improved outcome in the treatment of pediatric multifocal Langerhans cell histiocytosis
复制标题
改善儿童多灶性朗格汉斯细胞组织细胞增多症的治疗效果
作者：
A. Morimoto;S. Ikushima;N. Kinugawa;E. Ishii;U. Kohdera;M. Sako;J. Fujimoto;F. Bessho;K. Horibe;Y. Tsunematsu;S. Imashuku
多灶性儿童郎格罕细胞组织细胞增生症（LCH）的治疗结果并不令人满意，导致治疗反应差，死亡率高，复发率高，晚期后遗症。为了克服这些问题，日本LCH研究组-96（JLSG-96）方案于1996年至2001年在日本进行了前瞻性研究。
The treatment outcome of multifocal childhood Langerhans cell histiocytosis (LCH) has not been satisfactory and has resulted in poor therapeutic responses with high mortality and a high incidence of reactivation with late sequelae. To overcome these issues, the Japan LCH Study Group‐96 (JLSG‐96) protocol was conducted prospectively from 1996 to 2001 in Japan.