A model for intradendritic computation of binocular disparity

A model for intradendritic computation of binocular disparity
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DOI:
10.1038/71125
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发表时间:
2000-01-01
影响因子:
25
通讯作者:
Mel, BW
Mel, BW
中科院分区:
医学1区
文献类型:
--
作者:
Archie, KA;Mel, BW

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哺乳动物初级视觉皮层中的许多复杂细胞都针对双眼视差进行了微调。在流行的模型中,几个双目简单单元驱动每个视差调整的复杂单元。然而,一些猫科复合细胞接受直接 LGN 输入,而双眼简单细胞在猕猴中很少见。在我们的生物物理详细隔室模型中,单个神经元的活跃树突执行多个简单细胞状亚基计算,这些计算是方向和视差调整的基础。我们的详细模型的响应可以通过与“能量”模型密切相关的简单代数公式来预测。添加抑制性突触会导致更清晰、对比度不变的调谐曲线。因此,活跃的树突可能有助于复杂细胞中双眼视差的调节。
Many complex cells in mammalian primary visual cortex are finely tuned to binocular disparity. in the prevailing model, several binocular simple cells drive each disparity-tuned complex cell. However, some cat complex cells receive direct LGN input, and binocular simple cells are rare in macaque. In our biophysically detailed compartmental model, active dendrites of a single neuron perform the multiple simple-cell-like subunit computations that underlie both orientation and disparity tuning. The responses of our detailed model could be predicted by a simple algebraic formula closely related to an 'energy' model. Adding inhibitory synapses led to sharper, more contrast-invariant tuning curves. Thus active dendrites could contribute to binocular-disparity tuning in complex cells.