Time to development of symptomatic urinary calculi in a high risk environment

Time to development of symptomatic urinary calculi in a high risk environment
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DOI:
10.1097/01.ju.0000152578.07262.1c
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发表时间:
2005-03-01
期刊:
影响因子:
6.6
通讯作者:
Costabile, RA
Costabile, RA
中科院分区:
医学1区
文献类型:
--
作者:
Evans, K;Costabile, RA

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目的:虽然结石病的季节性变化已得到很好的描述,但泌尿系结石形成的时间尚不清楚。由于西南亚是结石病的高风险环境,因此进入该地区的日期是泌尿系结石风险增加时期的明确开始。最近国防部人员涌入西南亚,为在结石形成风险明确的时期内观察一组健康人员的结石病提供了机会。材料和方法:为 2003 年 3 月至 8 月部署在科威特的一家军事医院就诊的所有患有症状性泌尿系结石的患者建立了数据库。患者人口统计、结石特征和症状性泌尿系结石形成的时间 结果:共有 182 名患者被诊断出 218 颗有症状的结石。有症状的泌尿系结石形成的平均时间为 93 天,标准差为 42 天。结论:这项研究提供了有关高风险环境中症状性泌尿系结石发展的前所未有的信息。虽然人口、环境和医疗系统的独特方面为研究结石病创造了独特的机会,但这项研究的结果适用于一般人群。
Purpose: While seasonal variation of stone disease is well described, the time to formation of urinary calculi is unknown. Because southwestern Asia is a high risk environment for stone disease, the date of entry into this region is a definitive beginning to a period of increased risk of urinary calculi. The recent influx of Department of Defense personnel into southwestern Asia provided the opportunity to observe stone disease in a cohort of healthy personnel during a well-defined period of increased risk of stone formation.Materials and Methods: A database was constructed for all patients presenting with symptomatic urinary calculi to a single military hospital deployed to Kuwait from March through August 2003. Patient demographics, stone characteristics and time to formation of symptomatic urinary calculi were evaluated.Results: A total of 182 patients were diagnosed with 218 symptomatic stones. Mean time to formation of symptomatic urinary calculi was 93 days with a standard deviation of 42 days.Conclusions: This study provides unprecedented information about the development of symptomatic urinary calculi in a high risk environment. While unique aspects of the population, environment and medical system created a singular opportunity to study stone disease, the results of this study are applicable to the general population.