Preparation of high-quality graphene oxide-carbon quantum dots composites and their application for electrochemical sensing of uric acid and ascorbic acid
Preparation of high-quality graphene oxide-carbon quantum dots composites and their application for electrochemical sensing of uric acid and ascorbic acid
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DOI：
10.1088/1361-6528/abd12a
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发表时间：
2021-03-26
期刊：
影响因子：
3.5
通讯作者：
Liang, Zhengyong
中科院分区：
文献类型：
--
作者：
Ding, Ling;He, Huan;Liang, Zhengyong
氧化石墨烯-量子点系统正在成为一类新型材料，有望在生化传感应用中发挥作用。本文以廉价且可回收的焦炭粉为碳源，制备了环保型碳量子点（CQD）。以氧化石墨烯为导电骨架，通过一步煅烧法负载CQDs，合成了氧化石墨烯-碳量子点（GO-CQDs）复合材料。所获得的 GO-CQDs 复合材料证明了 CQDs 在 GO 纳米片上的成功装饰。作为间隔物的 CQD 在 GO 片之间产生间隙，从而产生高表面积，从而选择性地增加电解质的可及性和电子传输。通过调节GO与CQDs的质量比和加热过程，可以有效增强GO-CQDs复合材料的电催化活性和可逆性。此外，通过将 GO-CQDs 复合材料修饰到玻碳电极上，开发了一种用于测定尿酸（UA）和抗坏血酸（AA）的高灵敏度和选择性电化学传感器。结果表明，GO-CQDs电极检测UA的线性范围、最低检出限和灵敏度分别为1~150 μM、0.01 μM和2319.4 μ A mM(-1) cm(-2)，检测AA的线性范围、最低检出限和灵敏度分别为800~9000 μM、31.57 μM和53.1 μA mM(-1)。分别为厘米(-2)。采用GO-CQD作为电极材料进行血清和尿液样品电化学传感，结果表明该传感器可用于实际生物样品的分析。
Graphene oxide-quantum dots systems are emerging as a new class of materials that hold promise for biochemical sensing applications. In this paper, the eco-friendly carbon quantum dots (CQDs) are prepared with cheap and recyclable coke powders as carbon source. The graphene oxide-carbon quantum dots (GO-CQDs) composites are synthesized using graphene oxide as the conductive skeleton to load the CQDs by a one-step calcination method. The obtained GO-CQDs composites demonstrate the successful decoration of CQDs on GO nanosheets. The CQDs acting as spacers create gaps between GO sheets, resulting in a high surface area, which electively increases the electrolyte accessibility and electronic transmission. The electrocatalytic activity and reversibility of GO-CQDs composites can be effectively enhanced by tuning the mass ratio of GO to CQDs and the heating process. Furthermore, a highly sensitive and selective electrochemical sensor for determining uric acid (UA) and ascorbic acid (AA) was developed by modifying GO-CQDs composites onto a glassy carbon electrode. The results show that the linear range, minimum detection limit, and sensitivity of the GO-CQDs electrode for UA detection are 1-150 mu M, 0.01 mu M, and 2319.4 mu A mM(-1) cm(-2), respectively, and those for AA detection are 800-9000 mu M, 31.57 mu M, and 53.1 mu A mM(-1) cm(-2), respectively. The GO-CQDs are employed as the electrode materials for the serum and urine samples electrochemical sensing, the results indicate that the sensor can be used for the analysis of real biological samples.