Faces and objects in macaque cerebral cortex
Faces and objects in macaque cerebral cortex
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DOI：
10.1038/nn1111
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发表时间：
2003-09-01
影响因子：
25
通讯作者：
Tootell, RBH
中科院分区：
文献类型：
--
作者：
Tsao, DY;Freiwald, WA;Tootell, RBH
视觉系统如何组织不同的物体类别？目前的证据表明，猴子和人类处理对象类别的方式根本不同。功能性磁共振成像（fMRI）研究表明，人类有一个腹侧颞面部区域，但猕猴缺乏这样的证据。相反，猕猴的面部反应神经元似乎分散在整个颞叶皮层，在上级颞沟（STS）的一些相对集中。在这里，使用fMRI在警觉注视猕猴和人类中，我们发现猕猴确实有离散的面部选择性斑块，在相对大小和数量上与人类的面部斑块相似。面部贴片嵌入在从V4延伸到喙TE的对象选择性皮层的大片区域内。与杂乱物体相比，这个大区域对完整物体的图片反应更好，不同的物体类别引发不同的活动模式，就像人类一样。总的来说，我们的研究结果表明，人类和猕猴在视觉对象处理方面有着相似的大脑结构。
How are different object categories organized by the visual system? Current evidence indicates that monkeys and humans process object categories in fundamentally different ways. Functional magnetic resonance imaging (fMRI) studies suggest that humans have a ventral temporal face area, but such evidence is lacking in macaques. Instead, face-responsive neurons in macaques seem to be scattered throughout temporal cortex, with some relative concentration in the superior temporal sulcus (STS). Here, using fMRI in alert fixating macaque monkeys and humans, we found that macaques do have discrete face-selective patches, similar in relative size and number to face patches in humans. The face patches were embedded within a large swath of object-selective cortex extending from V4 to rostral TE. This large region responded better to pictures of intact objects compared to scrambled objects, with different object categories eliciting different patterns of activity, as in the human. Overall, our results suggest that humans and macaques share a similar brain architecture for visual object processing.