Analysis of the population genetic structure of the malaria vector Anopheles sinensis in south Korea based on mitochondrial sequences

Analysis of the population genetic structure of the malaria vector Anopheles sinensis in south Korea based on mitochondrial sequences
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DOI:
10.4269/ajtmh.2007.77.310
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发表时间:
2007-08-01
影响因子:
3.3
通讯作者:
Kim, Won
Kim, Won
中科院分区:
医学4区
文献类型:
--
作者:
Jung, Jongwoo;Jung, Yunjung;Kim, Won

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根据线粒体控制区238 bp可变区的核苷酸序列,对韩国主要疟疾媒介中华按蚊的种群遗传学进行了研究。观察到三个遗传方差特征。首先,太白山脉和Sobaek山脉可能是北方群(NG)和南方群(SG)之间的遗传屏障。这些山脉与人口的细分,并观察到显着的和独特的人口分化的研究领域。第二,在每个群体中观察到的遗传凝聚力可能是由最近的人口扩张而不是经常性的基因流动造成的。第三,两个群体之间遗传多样性的显著差异也可能是由几个因素造成的,这些因素导致了有效种群规模的差异。
The population genetics of Anopheles sinensis, a major malaria vector in South Korea, was studied based on the nucleotide sequences of a 238-bp variable region of the mitochondrial control region. Three features of genetic variance were observed. First, the Taebaek and Sobaek mountain ranges may function as genetic barriers between the Northern Group (NG) and the Southern Group (SG). These mountain ranges are associated with the subdivision of the population, and significant and unique population differentiation was observed in the examined area. Second, the genetic cohesiveness observed within each group may have been caused by a recent expansion in the population rather than recurrent gene flow. Third, a marked dissimilarity in the genetic diversity between the two groups may also have resulted from several factors that caused a difference in the effective population sizes.