Pathological changes in cattle naturally infected by Calicophoron daubneyi adult flukes
Pathological changes in cattle naturally infected by Calicophoron daubneyi adult flukes
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DOI：
10.1016/j.vetpar.2015.02.034
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发表时间：
2015-04-30
影响因子：
2.6
通讯作者：
Carmen Ferreras, M.
中科院分区：
文献类型：
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作者：
Fuertes, Miguel;Perez, Valentin;Carmen Ferreras, M.
研究了患有牛副蛔虫病的牛的前胃、皱胃、十二指肠和区域淋巴结中的局部宿主反应和寄生虫分布。发现寄生虫通过其腹侧吸盘附着在瘤胃和网状的小圆锥形乳头上。受影响的乳头表现出形态变化，表现为非常狭窄的茎和扩大的头部。在组织学上，这些变化的特征是上皮棘皮肥大-角化过度。炎症细胞的浸润常与上皮的变化有关，十二指肠粘膜和粘膜下层也有炎症细胞的浸润。这些细胞排列成聚集体或滤泡，但在固有层中也观察到嗜酸性粒细胞、小球白细胞、肥大细胞或巨噬细胞的稀疏浸润。瘤胃心房的组织损伤和炎症反应更为严重，其中观察到的吸虫和受影响的乳头数量最多。相反，瘤胃背囊中的病变不存在或轻微。病变严重程度和寄生虫负荷之间的统计相关性得到了证实。 (C) 2015 年由 Elsevier B.V. 出版
Local host response and parasite distribution were studied in the forestomachs, abomasum, duodenum and regional lymph nodes of cattle suffering from bovine paramphistomosis. The parasites were found attached, by its ventral sucker, to small conical papillae of the rumen and reticulum. Affected papillae, showed morphological changes denoted by very narrow stalks and expanded heads. Histologically, these changes were characterized by epithelial acanthosis-hyperkeratosis of the epithelium. Infiltration of inflammatory cells was often related with the epithelial changes, although it was also found in the duodenal mucosa and submucosa. These cells were arranged as aggregates or follicles but sparse infiltration of eosinophils, globule leukocytes, mast cells or macrophages was also observed in the lamina propria. Tissue damage and inflammatory reaction were more severe in the ruminal atrium, where the largest number of flukes and affected papillae were observed. In contrast, lesions in the ruminal dorsal sac were absent or mild. Statistical correlation between lesion severity and parasite burden was confirmed. (C) 2015 Published by Elsevier B.V.